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Article
Nature 227, 563-567 (8 August 1970) | doi:10.1038/227563a0; Received 10 July 1970
Characterization of the Products of RNA-directed DNA Polymerases in Oncogenic RNA Viruses
S. SPIEGELMAN, A. BURNY, M. R. DAS, J. KEYDAR, J. SCHLOM, M. TRAVNICEK & K. WATSON
- Institute of Cancer Research, Columbia University, and College of Physicians and Surgeons, 99 Fort Washington Avenue, New York, NY 10032
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Abstract
Several RNA tumour viruses contain an enzyme that synthesizes a DNA–RNA hybrid using the single stranded viral RNA as template. Hybridization experiments confirm that the DNA strand is complementary to the viral RNA.
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