Abstract
ANTI-LYMPHOCYTE serum (ALS) has been shown to have a significant suppressive effect on cell-mediated immune processes such as rejection of skin-homografts1,2. Suppression of humoral antibody formation by ALS has also been reported3. Moller and Zukoski4 have recently suggested that there may be a preferential effect of ALS on antigen-sensitive cells as compared with the antibody-producing cells. The mechanism underlying these various effects, however, is still a matter of conjecture. Studies of the effect of ALS on the target cell, the lymphocyte, therefore assume importance.
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PHONDKE, G., SUNDARAM, K. & SUNDARESAN, P. Effect of Anti-lymphocyte Serum on the Electrophoretic Mobility of the Lymph Node Cells of the Rat. Nature 225, 79–80 (1970). https://doi.org/10.1038/225079a0
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DOI: https://doi.org/10.1038/225079a0
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