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Homeostasis and Differentiation in Random Genetic Control Networks

Abstract

THE genome is a complex net of interacting components commonly thought to control homeostasis and differentiation through precisely constructed control circuits among the genes1–6. But I have found what seems to be a new class of dynamically stable systems, which suggests that even haphazardly constructed control nets of high molecular specificity undergo homeostasis and differentiation.

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KAUFFMAN, S. Homeostasis and Differentiation in Random Genetic Control Networks. Nature 224, 177–178 (1969). https://doi.org/10.1038/224177a0

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