Abstract
DURING investigations on the effect of streptomycin on the protein synthesis in Mycobacteria, it was observed that streptomycin inhibited the incorporation of 14C-DL-tyrosine into the protein of resting cells of a streptomycin-sensitive strain of Mycobacterium friburgensis while it had no such effect on the resistant strain (Table 1).
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References
Hoagland, M. B., Stephenson, M. L., Scott, J. F., Hecht, L. I., and Zamecnik, P. C., J. Biol. Chem., 231, 241 (1958).
Keller, E. B., and Zamecnik, P. C., J. Biol. Chem., 221, 45 (1956).
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ERDŐS, T., ULLMANN, A. Effect of Streptomycin on the Incorporation of Amino-Acids labeled with Carbon-14 into Ribonucleic Acid and Protein in a Cell-free System of a Mycobacterium . Nature 183, 618–619 (1959). https://doi.org/10.1038/183618a0
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DOI: https://doi.org/10.1038/183618a0
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