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Nature 182, 1310 - 1311 (08 November 1958); doi:10.1038/1821310a0

Effect of Hydrogen Peroxide on Transplanted Rat and Mouse Tumours


Sloan-Kettering Institute for Cancer Research, New York.

RECENTLY, Holman1 has reported that daily continued oral administration of commercial hydrogen peroxide (in drinking water) caused complete regression of Walker carcinoma 256 in rats in 50–60 per cent of the cases. This laboratory finding was applied in humans with advanced inoperable cancers. In two of the four cases there was reported a definite subjective and objective improvement1. The obvious importance of these findings in the case of a compound so plentiful made it desirable to attempt to confirm these results in Walker carcinoma 256 and in several of other animal tumours.

  1. Holman, R. A. , Nature, 159, 1023 (1957).
  2. Sugiura, K. , and Stock, C. C. , Cancer, 5, 382 (1952). | PubMed | ISI | ChemPort |
  3. Sugiura, K. , Cancer Research, 13, 431 (1953). | PubMed | ISI | ChemPort |

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