Single-Fibre Response from an Intact Animal

Abstract

IT is rather difficult to obtain electrical records of the activity of a single nerve fibre, because there are usually present some hundreds of other nerve fibres the contribution of which must be eliminated, and because the shunting of the active fibre by inert tissues or tissue fluid reduces the available action potential to vanishing proportions. It is therefore essential in most cases that the recorded fibre be fairly well isolated both physiologically and electrically, and we are not aware that any records have hitherto been published showing single fibre responses obtained from an animal which has not been dissected nor operated upon in any way.