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Chemical Nature of Proliferation-Promoting Factors from Injured Cells

Abstract

WE have published investigations indicating that yeast1 and animal cells2 injured by ultra-violet light and other means produce factors ('intercellular wound hormones')3 which are apparently released by injured, but living, cells into the intercellular fluid and stimulate the proliferation of normal cells. Spectrographic and chemical studies indicate that the active materials from yeast contain nucleic acid derivatives, as previously suggested4.

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LOOFBOUROW, J., COOK, E. & STIMSON, M. Chemical Nature of Proliferation-Promoting Factors from Injured Cells. Nature 142, 573–574 (1938). https://doi.org/10.1038/142573b0

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