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Molecular Shape and Size of Thymonucleic Acid

Nature volume 141, page 122 (1938)Cite this article

Abstract

A STUDY has been made of the viscosity and the double refraction of flow of thymonucleic acid in water solution. The sodium salt of the acid was prepared according to the method of Hammarsten1, and by high-pressure filtration cleared of the remaining few particles of denatured protein2, so that the solution could be studied by optical methods. The hydrodynamic relations between internal friction and particle size of rod-suspensions3 and the observations on double refraction of flow4 permit the following conclusions from the data:

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References

  1. Biochem. Z., 144, 386 (1924).

  2. Caspersson, T., Biochem. Z., 270, 161 (1934).

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  3. Burgers, J. M., Second Report on Viscosity and Plasticity. Verhand. Nederl. Kon. Akademie v. Wetenschappen te Amsterdam, Afd. Natuurkunde, 1937.

  4. Signer, R., Trans. Farad. Soc., 32, 296 (1936).

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  5. Hammarsten, E. and Hammarsten, H., and Caspersson, T., Trans. Farad. Soc., 31, 367 (1935).

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  6. Caspersson, T., Skand. Arch. Physiol., 73, Suppl. 8 (1936).

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Authors and Affiliations

  1. Department of Chemistry, University, Bern,

    R. SIGNER

  2. Department of Chemistry, Caroline Institute, Stockholm

    T. CASPERSSON & E. HAMMARSTEN

Authors
  1. R. SIGNER
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  2. T. CASPERSSON
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  3. E. HAMMARSTEN
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SIGNER, R., CASPERSSON, T. & HAMMARSTEN, E. Molecular Shape and Size of Thymonucleic Acid. Nature 141, 122 (1938). https://doi.org/10.1038/141122a0

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