Browse Articles

  • Editorial |

    Efficient redox catalysis offers an important avenue in using renewable energy to process fuels. To this end, efforts in homogeneous, heterogeneous and microbial catalysis may each advance our fundamental understanding and technological capabilities.

  • Review Article |

    Bio-interface materials inspired by natural systems that respond efficiently to various external stimuli can dynamically regulate molecular interactions between biological entities and material surfaces. In this Review, Gomes and colleagues describe advances in bio-interface materials that may provide insights into cell behaviour, biofouling and the production of on-demand devices with medical applications, among others.

    • Bárbara Santos Gomes
    • , Bárbara Simões
    •  & Paula M. Mendes
  • Review Article |

    Quantum electrodynamics (QED) is the most complete theoretical framework to date to complement experimental spectroscopies in chemistry. Owing to its complexity, several approximations are needed in order to be able to apply QED in practice. This Review highlights how the breakdown of some of these approximations challenges our understanding of light–matter interactions and discusses how new theoretical developments can help to overcome these approximations.

    • Michael Ruggenthaler
    • , Nicolas Tancogne-Dejean
    • , Johannes Flick
    • , Heiko Appel
    •  & Angel Rubio
  • In the Classroom |

    Lecture capture is just one way in which new technology is changing teaching, but we should embrace its opportunities rather than fear its shortcomings, argues Katherine Haxton.

    • Katherine Haxton
  • Review Article |

    The approximation underlying most atomistic simulations to treat nuclei classically can lead to large errors and the failure to capture important physical effects. This Review reports on recent developments that enable modelling of quantum nuclei at a computational cost comparable with that of a classical simulation.

    • Thomas E. Markland
    •  & Michele Ceriotti
  • Review Article |

    The design of synthetic systems that mimic the ability of biological systems to control chemical reactions using intricate molecular machines is a long-held dream of nanotechnology. This Review discusses how developments in controlled molecular switching and movement are being exploited in the design of catalysts that are just beginning to emulate the complexity of living systems.

    • Lucy van Dijk
    • , Michael J. Tilby
    • , Robert Szpera
    • , Owen A. Smith
    • , Holly A. P. Bunce
    •  & Stephen P. Fletcher
  • Research Highlight |

    Phosphonium adducts of pyridines are labile in basic solution, an undesirable property with regard to organic synthesis. Yet, this very lability proves valuable for the labelling of pyridine and diazines with heavier isotopes of hydrogen.

    • Andrew Bissette
  • Research Highlight |

    Electrocatalytic O2 reduction on metal surfaces is well understood in acidic solution, but the mechanism in basic solution has been a point of contention. On studying the O2 reduction activities of a series of Pt(111)–Cu surface alloys, it becomes clear that the surface-bound oxygenic intermediates are the same regardless of the pH.

    • David Schilter
  • Review Article |

    The metals in polyoxometalates need not be in their highest oxidation states. Indeed, polyoxometalates can exist in reduced forms, and several different metals can be incorporated into various structural archetypes. This Review describes the synthesis and characterization of these complexes, along with their topical catalytic, electronic and biological properties.

    • Nadiia I. Gumerova
    •  & Annette Rompel
  • Review Article |

    Iterative approaches to synthesis have revolutionized the preparation and study of peptides, nucleic acids and sugars. This Review discusses whether and how such iterative syntheses can be applied more broadly towards an ultimate goal of developing a building block approach to the synthesis of most small organic molecules.

    • Jonathan W. Lehmann
    • , Daniel J. Blair
    •  & Martin D. Burke
  • Review Article |

    Building on the theoretical prediction and experimental realization of planar tetracoordinate carbons, there has been great progress in the theoretical prediction of species containing planar pentacoordinate carbon (ppC) centres. From simple clusters such as CAl5+ to complicated ppCs in 2D materials, this Review summarizes the ppC-containing species predicted to date and the design principles behind them.

    • Valentin Vassilev-Galindo
    • , Sudip Pan
    • , Kelling J. Donald
    •  & Gabriel Merino
  • Research Highlight |

    The first detection of rotational features of benzonitrile offers the opportunity to undesrtand the origin of PAHs in space.

    • Gabriella Graziano
  • Research Highlight |

    The practicality of radical polymerizations is limited by their sensitivity to O2. This inhibitor can be enzymatically degraded into H2O2, which is scavenged by pyruvate as part of a new atom transfer radical polymerization (ATRP) methodology.

    • Johannes Kreutzer
  • Review Article |

    The electrochemical oxidation and reduction of water and carbon dioxide are associated with the release or storage of energy. This Review reports the latest developments in the design and use of low-dimensional materials and their van der Waals heterostructures for electrocatalytic and photocatalytic hydrogen evolution and CO2 conversion.

    • Damien Voiry
    • , Hyeon Suk Shin
    • , Kian Ping Loh
    •  & Manish Chhowalla
  • Editorial |

    We give our perspective on one year of publishing Nature Reviews Chemistry.

  • Research Highlight |

    Semiconductor nanocrystals absorb light and are involved in energy transfer to and from surface chromophores. Tuning the nanocrystal- and chromophore-centred exciton energies affords exquisite control over an excited-state equilibrium.

    • David Schilter
  • Review Article |

    Some plant-derived ligands for the cannabinoid receptors — phytocannabinoids — are promising pharmaceuticals. This Review covers the chemical synthesis of phytocannabinoids and metabolites to enable the study of compounds otherwise inaccessible on a practical scale. Availability of drug candidates is also hindered by policy issues, which we discuss with regard to possession, use and control.

    • Tristan A. Reekie
    • , Michael P. Scott
    •  & Michael Kassiou
  • Perspective |

    Numerous fabrication methods have been developed so far for the production of graphenes and nanographenes. However, how practical is the bulk production of these fascinating materials? This Perspective discusses recent advances in graphene fabrication and possibilities for translation to large-scale production.

    • Xiao-Ye Wang
    • , Akimitsu Narita
    •  & Klaus Müllen
  • Perspective |

    Metal–ligand cooperative catalysis involves both the metal and the ligand moieties present in a complex interacting with substrates. Cooperative catalysis is central to the mechanisms of hydrogenases, lactate racemase and alcohol dehydrogenase. This Perspective describes these enzymes, as well as the small-molecule mimics inspired by these elaborate natural catalysts.

    • Matthew D. Wodrich
    •  & Xile Hu
  • Review Article |

    Electrocatalysts for the oxygen reduction reaction are important components of energy technologies such as fuel cells. The study of molecular catalysts affords mechanistic insights that further the development of robust, active and energy-efficient systems. This Review describes state-of-the-art metal complexes that operate either in solution or immobilized on an electrode.

    • Subal Dey
    • , Biswajit Mondal
    • , Sudipta Chatterjee
    • , Atanu Rana
    • , Sk Amanullah
    •  & Abhishek Dey