Reviews & Analysis

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  • Tumour necrosis factor is a classical pro-inflammatory cytokine. Sethi and Hotamisligil provide a comprehensive overview of its pleiotropic immunometabolic actions, while presenting a framework that is applicable to the complex network of other pro-inflammatory signals and their relevance to metabolic diseases such as obesity and diabetes.

    • Jaswinder K. Sethi
    • Gökhan S. Hotamisligil
    Metabolic Messengers
  • Flippo and Potthoff provide a concise overview of the major physiological and pharmacological effects of FGF21 in nutrient and energy homeostasis.

    • Kyle H. Flippo
    • Matthew J. Potthoff
    Metabolic Messengers
  • Gribble and Reimann provide a concise overview of the core physiology of GLP-1 secretion and action, and the roles of GLP-1 in human health, disease and therapy.

    • Fiona M. Gribble
    • Frank Reimann
    Metabolic Messengers