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Dive and colleagues develop an approach for genome-wide cell-free DNA methylation profiling, which can sensitively detect small cell lung cancer in liquid biopsy of patient samples, including stage I disease and molecularly defined SCLC subtypes.
Danko and colleagues develop BayesPrism, a bulk RNA sequencing deconvolution tool to infer cell type composition and cell-specific expression levels across clinical cancer datasets.
Tamborero and colleagues develop the Molecular Tumor Board Portal, a virtual platform that integrates and interprets genomics and clinical data from prospective clinical studies, to support clinical decision-making for precision oncology.