Molecular Psychiatry

Volume 26 Issue 7, July 2021

Immunofl uorescent staining of rat primary neurons (DIV. 14). Images show neuronal TrkB and APP co-localized on the cell surface. Neurons are labeled green with APP, red with TrkB, and blue with DAPI. For more information see the article by Yiyuan Xia et al. on page 2943–2963.

Volume 26 Issue 7

Image

The MSDB sends a GABAergic projection to cholinergic neurons in the ventral MHb

Casey R. Vickstrom
Xiaojie Liu
Qing-song Liu
Image 15 Sept 2021
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Correspondence

Leveraging aggression risk gene expression in the developing and adult human brain to guide future precision interventions

Ahra Kim
Sarah L. Rader
Alan S. Lewis
Correspondence 12 Oct 2020
GABA_B receptor, clozapine, and catatonia—a complex triad

Dusan Hirjak
Georg Northoff
Robert Christian Wolf
Correspondence 25 Sept 2020

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Review Article

Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders

Aurélie de Rus Jacquet
Hélèna L. Denis
Melanie Alpaugh
Review Article 25 Jan 2021

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Correction

Correction to: Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders

Aurélie de Rus Jacquet
Hélèna L. Denis
Melanie Alpaugh
Correction Open Access 09 Mar 2021

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Expert Review

Vitamin D and schizophrenia: 20 years on

Xiaoying Cui
John J. McGrath
Darryl W. Eyles
Expert Review Open Access 26 Jan 2021

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Immediate Communication

The translocator protein (TSPO) is prodromal to mitophagy loss in neurotoxicity

Michele Frison
Danilo Faccenda
Michelangelo Campanella
Immediate Communication Open Access 04 Mar 2021
Ucp2-dependent microglia-neuronal coupling controls ventral hippocampal circuit function and anxiety-like behavior

Yuki Yasumoto
Milan Stoiljkovic
Tamas L. Horvath
Immediate Communication 20 Apr 2021
Sensing serotonin secreted from human serotonergic neurons using aptamer-modified nanopipettes

Nako Nakatsuka
Kelly J. Heard
Krishna C. Vadodaria
Immediate Communication 25 Mar 2021
Structural brain measures linked to clinical phenotypes in major depression replicate across clinical centres

Meichen Yu
Nicholas Cullen
Yvette I. Sheline
Immediate Communication 15 Feb 2021
Precision medicine for mood disorders: objective assessment, risk prediction, pharmacogenomics, and repurposed drugs

H. Le-Niculescu
K. Roseberry
A. B. Niculescu
Immediate Communication Open Access 08 Apr 2021

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Article

ADORA₁-driven brain-sympathetic neuro-adipose connections control body weight and adipose lipid metabolism

Jia Zhang
Yanjun Hou
Yunlei Yang
Article 16 Oct 2020
Reconsolidation of a post-ingestive nutrient memory requires mTOR in the central amygdala

Yuhua Yan
Lingli Zhang
Fei Li
Article 01 Sept 2020
Reciprocal control of obesity and anxiety–depressive disorder via a GABA and serotonin neural circuit

Guobin Xia
Yong Han
Qi Wu
Article Open Access 26 Mar 2021
Sialylated human milk oligosaccharides program cognitive development through a non-genomic transmission mode

Jonas Hauser
Edoardo Pisa
Simone Macrì
Article Open Access 04 Mar 2021
Identification of Neurensin-2 as a novel modulator of emotional behavior

Gali Umschweif
Lucian Medrihan
Paul Greengard

Collection:

2021 Highlights from MP
Article Open Access 19 Mar 2021
STAT3 in the dorsal raphe gates behavioural reactivity and regulates gene networks associated with psychopathology

Sonali N. Reisinger
Spyros Sideromenos
Daniela D. Pollak
Article Open Access 12 Oct 2020
Functional deletion of neuropeptide Y receptors type 2 in local synaptic networks of anteroventral BNST facilitates recall and increases return of fear

Julia Constance Bartsch
Sara Jamil
Hans-Christian Pape
Article Open Access 24 Jul 2020
Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway

Ya-Dong Li
Yan-Jia Luo
Zhi-Li Huang
Article Open Access 14 Oct 2020
Consequences of NMDA receptor deficiency can be rescued in the adult brain

Catharine A. Mielnik
Mary A. Binko
Amy J. Ramsey
Article Open Access 17 Aug 2020
TrkB receptor cleavage by delta-secretase abolishes its phosphorylation of APP, aggravating Alzheimer’s disease pathologies

Yiyuan Xia
Zhi-Hao Wang
Keqiang Ye
Article 11 Aug 2020
Human cerebral organoids establish subcortical projections in the mouse brain after transplantation

Xin Dong
Shi-Bo Xu
Yan Liu
Article Open Access 13 Oct 2020
Genetic association of FMRP targets with psychiatric disorders

Nicholas E. Clifton
Elliott Rees
Andrew J. Pocklington
Article Open Access 19 Oct 2020
Identifying and validating subtypes within major psychiatric disorders based on frontal–posterior functional imbalance via deep learning

Miao Chang
Fay Y. Womer
Fei Wang
Article Open Access 01 Oct 2020

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Correction

Correction: Identifying and validating subtypes within major psychiatric disorders based on frontal–posterior functional imbalance via deep learning

Miao Chang
Fay Y. Womer
Fei Wang
Correction Open Access 17 Nov 2020

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Article

Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia

Alessandro Gialluisi
Till F. M. Andlauer
Gerd Schulte-Körne
Article Open Access 14 Oct 2020
Brexpiprazole blocks post-traumatic stress disorder-like memory while promoting normal fear memory

Eva-Gunnel Ducourneau
Christelle Guette
Pier-Vincenzo Piazza
Article 19 Aug 2020
Omega-3 supplementation and stress reactivity of cellular aging biomarkers: an ancillary substudy of a randomized, controlled trial in midlife adults

Annelise A. Madison
Martha A. Belury
Janice K. Kiecolt-Glaser
Article 20 Apr 2021
Type 1 interferon mediates chronic stress-induced neuroinflammation and behavioral deficits via complement component 3-dependent pathway

Ashutosh Tripathi
Carl Whitehead
Anilkumar Pillai
Article 08 Apr 2021
The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice

Alexander S. Häusl
Lea M. Brix
Mathias V. Schmidt
Article Open Access 01 Mar 2021
Integration of peripheral transcriptomics, genomics, and interactomics following trauma identifies causal genes for symptoms of post-traumatic stress and major depression

Stefan Wuchty
Amanda J. Myers
Charles B. Nemeroff
Article 07 May 2021
Importance of sex and trauma context on circulating cytokines and amygdalar GABAergic signaling in a comorbid model of posttraumatic stress and alcohol use disorders

Michael Q. Steinman
Dean Kirson
Marisa Roberto
Article 21 Oct 2020
Socio-demographic and trauma-related predictors of PTSD within 8 weeks of a motor vehicle collision in the AURORA study

Ronald C. Kessler
Kerry J. Ressler
Samuel A. McLean
Article 19 Oct 2020
TSPAN5 influences serotonin and kynurenine: pharmacogenomic mechanisms related to alcohol use disorder and acamprosate treatment response

Ming-Fen Ho
Cheng Zhang
Richard Weinshilboum
Article Open Access 04 Aug 2020
Cocaine-related DNA methylation in caudate neurons alters 3D chromatin structure of the IRXA gene cluster

Kathryn Vaillancourt
Jennie Yang
Gustavo Turecki
Article 12 Oct 2020
Cocaine-induced neural adaptations in the lateral hypothalamic melanin-concentrating hormone neurons and the role in regulating rapid eye movement sleep after withdrawal

Yao Wang
Rong Guo
Yanhua H. Huang
Article 22 Oct 2020
Population-specific genetic background for the OPRM1 variant rs1799971 (118A>G): implications for genomic medicine and functional analysis

Orna Levran
Mary Jeanne Kreek
Article 09 Oct 2020
Role of endocannabinoid signaling in a septohabenular pathway in the regulation of anxiety- and depressive-like behavior

Casey R. Vickstrom
Xiaojie Liu
Qing-song Liu
Article 22 Oct 2020
Preliminary in vivo evidence of lower hippocampal synaptic density in cannabis use disorder

Deepak Cyril D’Souza
Rajiv Radhakrishnan
Patrick Skosnik
Article 24 Sept 2020
Re-examining the link between childhood maltreatment and substance use disorder: a prospective, genetically informative study

Andrea J. Capusan
Per A. Gustafsson
Markus Heilig
Article 06 Apr 2021

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Correction

Correction: Re-examining the link between childhood maltreatment and substance use disorder: a prospective, genetically informative study

Andrea J. Capusan
Per A. Gustafsson
Markus Heilig
Correction 30 Apr 2021

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Article

Preadult polytoxicomania—strong environmental underpinnings and first genetic hints

Agnes A. Steixner-Kumar
Vinicius Daguano Gastaldi
Hannelore Ehrenreich
Article Open Access 07 Apr 2021
The Rap1 small GTPase is a critical mediator of the effects of stress on prefrontal cortical dysfunction

B. A. Kermath
A. M. Vanderplow
M. E. Cahill
Article 10 Jul 2020
Adult-born neurons from the dorsal, intermediate, and ventral regions of the longitudinal axis of the hippocampus exhibit differential sensitivity to glucocorticoids

Brunno Rocha Levone
Martin G. Codagnone
Olivia F. O’ Leary
Article 24 Jul 2020
P11 deficiency increases stress reactivity along with HPA axis and autonomic hyperresponsiveness

Vasco C. Sousa
Ioannis Mantas
Per Svenningsson
Article Open Access 01 Oct 2020
In vitro model of perimenopausal depression implicates steroid metabolic and proinflammatory genes

Sarah Rudzinskas
Jessica F. Hoffman
David Goldman
Article 12 Aug 2020
Inhibition of GABA interneurons in the mPFC is sufficient and necessary for rapid antidepressant responses

Manoela V. Fogaça
Min Wu
Ronald S. Duman
Article 17 Oct 2020
Ketamine modulates fronto-striatal circuitry in depressed and healthy individuals

Anahit Mkrtchian
Jennifer W. Evans
Carlos A. Zarate Jr.
Article Open Access 14 Sept 2020
The longitudinal associations of inflammatory biomarkers and depression revisited: systematic review, meta-analysis, and meta-regression

Naoise Mac Giollabhui
Tommy H. Ng
Lauren B. Alloy
Article 17 Aug 2020
Associations of depression status with plasma levels of candidate lipid and amino acid metabolites: a meta-analysis of individual data from three independent samples of US postmenopausal women

Tianyi Huang
Raji Balasubramanian
Susan E. Hankinson
Article 28 Aug 2020
Network dynamics of depressive symptoms in antidepressant medication treatment: secondary analysis of eight clinical trials

Kaisla Komulainen
Jaakko Airaksinen
Markus Jokela
Article 16 Sept 2020
Distinct non-inflammatory signature of microglia in post-mortem brain tissue of patients with major depressive disorder

Gijsje J. L. J. Snijders
Marjolein A. M. Sneeboer
Lot D. de Witte
Article 07 Oct 2020
Activation of the p11/SMARCA3/Neurensin-2 pathway in parvalbumin interneurons mediates the response to chronic antidepressants

Gali Umschweif
Lucian Medrihan
Paul Greengard

Collection:

2021 Highlights from MP
Article Open Access 15 Mar 2021
Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

Chiara Fabbri
Saskia P. Hagenaars
Cathryn M. Lewis
Article Open Access 22 Mar 2021
Age, period, and cohort effects on suicide death in the United States from 1999 to 2018: moderation by sex, race, and firearm involvement

Gonzalo Martínez-Alés
John R. Pamplin II
Katherine M. Keyes
Article 07 Apr 2021
Circadian rhythms in bipolar disorder patient-derived neurons predict lithium response: preliminary studies

Himanshu K. Mishra
Noelle M. Ying
Michael J. McCarthy
Article 05 Mar 2021
Peripheral inflammatory biomarkers define biotypes of bipolar depression

Yena Lee
Rodrigo B. Mansur
Roger S. McIntyre
Article 03 Mar 2021
Decreased DNA methylation at promoters and gene-specific neuronal hypermethylation in the prefrontal cortex of patients with bipolar disorder

Miki Bundo
Junko Ueda
Kazuya Iwamoto
Article Open Access 20 Apr 2021
The kynurenine pathway in bipolar disorder: a meta-analysis on the peripheral blood levels of tryptophan and related metabolites

Francesco Bartoli
Błażej Misiak
Giuseppe Carrà
Article 19 Oct 2020
Multivariate relationships between peripheral inflammatory marker subtypes and cognitive and brain structural measures in psychosis

Paulo Lizano
Olivia Lutz
Jeffrey R. Bishop
Article 15 Oct 2020
Transcription factor POU3F2 regulates TRIM8 expression contributing to cellular functions implicated in schizophrenia

Chaodong Ding
Chunling Zhang
Chao Chen
Article 14 Sept 2020
Optogenetic manipulation of an ascending arousal system tunes cortical broadband gamma power and reveals functional deficits relevant to schizophrenia

James M. McNally
David D. Aguilar
Ritchie E. Brown
Article 20 Jul 2020
Dopamine dysregulation in psychotic relapse after antipsychotic discontinuation: an [¹⁸F]DOPA and [¹¹C]raclopride PET study in first-episode psychosis

Seoyoung Kim
Sang Ho Shin
Euitae Kim
Article 14 Sept 2020
Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes

Mélanie Druart
Marika Nosten-Bertrand
Corentin Le Magueresse
Article 09 Apr 2021
A multimodal approach to studying the relationship between peripheral glutathione, brain glutamate, and cognition in health and in schizophrenia

Jennifer M. Coughlin
Kun Yang
Akira Sawa
Article 19 Oct 2020
Individual deviations from normative models of brain structure in a large cross-sectional schizophrenia cohort

Jinglei Lv
Maria Di Biase
Andrew Zalesky
Article 22 Sept 2020
Hippocampal volume and hippocampal neuron density, number and size in schizophrenia: a systematic review and meta-analysis of postmortem studies

Maxwell J. Roeske
Christine Konradi
Alan S. Lewis
Article 28 Jul 2020
Single molecule in situ hybridization reveals distinct localizations of schizophrenia risk-related transcripts SNX19 and AS3MT in human brain

Yoichiro Takahashi
Kristen R. Maynard
Thomas M. Hyde
Article 01 Mar 2021
Impulsive prepotent actions and tics in Tourette disorder underpinned by a common neural network

Cyril Atkinson-Clement
Camille-Albane Porte
Yulia Worbe
Article Open Access 29 Sept 2020
Inositol monophosphatase 1 (IMPA1) mutation in intellectual disability patients impairs neurogenesis but not gliogenesis

Thalita Figueiredo
Ana P. D. Mendes
Mayana Zatz
Article 24 Aug 2020
Wnt/β-catenin pathway and cell adhesion deregulation in CSDE1-related intellectual disability and autism spectrum disorders

E. El Khouri
J. Ghoumid
I. Giurgea
Article 19 Apr 2021
Autism-linked Cullin3 germline haploinsufficiency impacts cytoskeletal dynamics and cortical neurogenesis through RhoA signaling

Megha Amar
Akula Bala Pramod
Lilia M. Iakoucheva
Article Open Access 16 Mar 2021
Cell-type-specific synaptic imbalance and disrupted homeostatic plasticity in cortical circuits of ASD-associated Chd8 haploinsufficient mice

Robert A. Ellingford
Martyna J. Panasiuk
Laura C. Andreae
Article Open Access 09 Apr 2021
Angelman syndrome genotypes manifest varying degrees of clinical severity and developmental impairment

Marius Keute
Meghan T. Miller
Joerg F. Hipp
Article Open Access 13 Aug 2020
Resting state network functional connectivity abnormalities in systemic lupus erythematosus: correlations with neuropsychiatric impairment

Raffaello Bonacchi
Maria A. Rocca
Massimo Filippi
Article 13 Oct 2020
Older molecular brain age in severe mental illness

Chien-Wei Lin
Lun-Ching Chang
Etienne Sibille
Article 06 Jul 2020

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Correction

Correction: Healthy dietary indices and risk of depressive outcomes: a systematic review and meta-analysis of observational studies

Camille Lassale
G. David Batty
Tasnime Akbaraly
Correction 04 Mar 2021
Correction: The AURORA Study: a longitudinal, multimodal library of brain biology and function after traumatic stress exposure

Samuel A. McLean
Kerry Ressler
Ronald Kessler
Correction 28 Sept 2020
Correction: Shared mechanisms between coronary heart disease and depression: findings from a large UK general population-based cohort

Golam M. Khandaker
Verena Zuber
Stephen Burgess
Correction Open Access 17 Aug 2020
Correction: Hippocampal neural stem cells and microglia response to experimental inflammatory bowel disease (IBD)

Ioannis-Alexandros Gampierakis
Yassemi Koutmani
Katia P. Karalis
Correction 01 Sept 2020
Correction to: Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality

María Soler Artigas
Cristina Sánchez-Mora
Marta Ribasés
Correction 24 Feb 2021

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Retraction

Retraction Note: p62 improves AD-like pathology by increasing autophagy

A. Caccamo
E. Ferreira
S. Oddo
Retraction Open Access 11 Aug 2020

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