Welcome to Molecular Psychiatry

Molecular Psychiatry publishes papers elucidating the biological mechanisms underlying psychiatric disorders and their treatment. The emphasis is on studies at the interface of pre-clinical and clinical research, including studies at the cellular, molecular, integrative, clinical, imaging and psychopharmacology levels.

Editor-in-Chief: Julio Licinio, MD; Impact Factor 5.538*

Translational Psychiatry, a sister journal to Molecular Psychiatry, is an online-only, open access publication that provides high quality research, a respected editorial team, rapid publication and high visibility. Visit http://www.nature.com/tp.


Check out the joint Molecular Psychiatry and Translational Psychiatry web focus, which features all articles authored by Nobel Laureates in these two journals! 

About the cover

Volume 22, No 6
June 2017

ISSN: 1359-4184
EISSN: 1476-5578

2015 Impact Factor 13.314*
4/140 Psychiatry
7/256 Neurosciences
7/289 Biochemistry & Molecular Biology

Julio Licinio, MD

*2015 Journal Citation Reports® Science Edition (Thomson Reuters, 2016)


Check out Molecular Psychiatry's recently published paper on stress-induced depression, co-authored by Nobel Laureate Paul Greengard!

Molecular Psychiatry was mentioned: A study published in Molecular Psychiatry provides evidence that children with lower socioeconomic status are more prone to mental illness. This study could with the development of strategies and personalized treatment for mental illness. Read the article or the news story!

An Immediate Communication in Molecular Psychiatry reports a molecular mechanism whereby NMDA receptor antagonists such as ketamine can increase mTOR signaling to elicit antidepressant actions. Drugs selectively targeting components of this pathway may offer novel approaches to the treatments of depression. Read the report now.

Molecular Psychiatry is now a member of the Neuroscience Peer Review Consortium (NPRC). The purpose of the NPRC is to decrease the time and effort involved in the peer review process, and reduce the burden placed on reviewers. NPRC member journals agree to transfer manuscript reviews upon the author's request. A flowchart of the transfer process and a list of member journals can be found on the NPRC website.

Visit Nature Publishing Group's open access funding page for information about research funders and institutions that provide funding for open access. NPG also offers an APC support service to make it easier for NPG authors to discover and apply for open access funding. For advice on what funding is available to you and help in approaching funders and institutions, please contact us at openaccess@nature.com.

Want to order a poster of a Molecular Psychiatry journal cover? If so, follow this link to the order form.


The Top Ten charts the articles that have been downloaded most often over the previous 30 days, in HTML and PDF format, from the Molecular Psychiatry website. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.

May 2017

  1. The microbiome regulates amygdala-dependent fear recall

    A E Hoban, R M Stilling, G Moloney, F Shanahan, T G Dinan, G Clarke & J F Cryan


    Abstract | Full Text | PDF

  2. Longitudinal changes of tau PET imaging in relation to hypometabolism in prodromal and Alzheimer’s disease dementia

    K Chiotis, L Saint-Aubert, E Rodriguez-Vieitez, A Leuzy, O Almkvist, I Savitcheva, M Jonasson, M Lubberink, A Wall, G Antoni & A Nordberg


    Abstract | Full Text | PDF

  3. Cortical abnormalities in bipolar disorder: an MRI analysis of 6503 individuals from the ENIGMA Bipolar Disorder Working Group

    D P Hibar, L T Westlye, N T Doan, N Jahanshad, J W Cheung, C R K Ching, A Versace, A C Bilderbeck, A Uhlmann, B Mwangi, B Krämer, B Overs, C B Hartberg, C Abé, D Dima, D Grotegerd, E Sprooten, E Bøen, E Jimenez, F M Howells, G Delvecchio, H Temmingh, J Starke, J R C Almeida, J M Goikolea, J Houenou, L M Beard, L Rauer, L Abramovic, M Bonnin, M F Ponteduro, M Keil, M M Rive, N Yao, N Yalin, P Najt, P G Rosa, R Redlich, S Trost, S Hagenaars, S C Fears, S Alonso-Lana, T G M van Erp, T Nickson, T M Chaim-Avancini, T B Meier, T Elvsåshagen, U K Haukvik, W H Lee, A H Schene, A J Lloyd, A H Young, A Nugent, A M Dale, A Pfennig, A M McIntosh, B Lafer, B T Baune, C J Ekman, C A Zarate, C E Bearden, C Henry, C Simhandl, C McDonald, C Bourne, D J Stein, D H Wolf, D M Cannon, D C Glahn, D J Veltman, E Pomarol-Clotet, E Vieta, E J Canales-Rodriguez, F G Nery, F L S Duran, G F Busatto, G Roberts, G D Pearlson, G M Goodwin, H Kugel, H C Whalley, H G Ruhe, J C Soares, J M Fullerton, J K Rybakowski, J Savitz, K T Chaim, M Fatjó-Vilas, M G Soeiro-de-Souza, M P Boks, M V Zanetti, M C G Otaduy, M S Schaufelberger, M Alda, M Ingvar, M L Phillips, M J Kempton, M Bauer, M Landén, N S Lawrence, N E M van Haren, N R Horn, N B Freimer, O Gruber, P R Schofield, P B Mitchell, R S Kahn, R Lenroot, R Machado-Vieira, R A Ophoff, S Sarró, S Frangou, T D Satterthwaite, T Hajek, U Dannlowski, U F Malt, V Arolt, W F Gattaz, W C Drevets, X Caseras, I Agartz, P M Thompson & O A Andreassen


    Abstract | Full Text | PDF

  4. Brain age predicts mortality

    J H Cole, S J Ritchie, M E Bastin, M C Valdés Hernández, S Muñoz Maniega, N Royle, J Corley, A Pattie, S E Harris, Q Zhang, N R Wray, P Redmond, R E Marioni, J M Starr, S R Cox, J M Wardlaw, D J Sharp & I J Deary


    Abstract | Full Text | PDF

  5. Genetics and intelligence differences: five special findings

    R Plomin & I J Deary


    Abstract | Full Text | PDF

  6. From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways

    G B Rogers, D J Keating, R L Young, M-L Wong, J Licinio & S Wesselingh


    Abstract | Full Text | PDF

  7. Preventing intrusive memories after trauma via a brief intervention involving Tetris computer game play in the emergency department: a proof-of-concept randomized controlled trial

    L Iyadurai, S E Blackwell, R Meiser-Stedman, P C Watson, M B Bonsall, J R Geddes, A C Nobre & E A Holmes


    Abstract | Full Text | PDF

  8. Disinhibition of somatostatin-positive GABAergic interneurons results in an anxiolytic and antidepressant-like brain state

    T Fuchs, S J Jefferson, A Hooper, P-HP Yee, J Maguire & B Luscher


    Abstract | Full Text | PDF

  9. Elevation of p11 in lateral habenula mediates depression-like behavior

    J-S Seo, P Zhong, A Liu, Z Yan & P Greengard


    Abstract | Full Text | PDF

  10. Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability

    L E Duncan, A Ratanatharathorn, A E Aiello, L M Almli, A B Amstadter, A E Ashley-Koch, D G Baker, J C Beckham, L J Bierut, J Bisson, B Bradley, C-Y Chen, S Dalvie, L A Farrer, S Galea, M E Garrett, J E Gelernter, G Guffanti, M A Hauser, E O Johnson, R C Kessler, N A Kimbrel, A King, N Koen, H R Kranzler, M W Logue, A X Maihofer, A R Martin, M W Miller, R A Morey, N R Nugent, J P Rice, S Ripke, A L Roberts, N L Saccone, J W Smoller, D J Stein, M B Stein, J A Sumner, M Uddin, R J Ursano, D E Wildman, R Yehuda, H Zhao, M J Daly, I Liberzon, K J Ressler, C M Nievergelt & K C Koenen


    Abstract | Full Text | PDF

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27 May 2017