Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
We present a comprehensive, up-to-date review of host-directed therapeutics (HDTs) to improve clinical outcome in tuberculosis (TB) disease, summarizing all compounds, primarily repurposed drugs, tested in human clinical trials. Where available, results from each phase of these investigations are discussed.
As a result of the significant disruption that is being caused by the COVID-19 pandemic we are very aware that many researchers with child care duties will have difficulty in meeting the timelines associated with our peer review process during normal times. Please do let us know if you need additional time. Our systems will continue to remind you of the original timelines but we intend to be highly flexible at this time.