ADVANCE ONLINE PUBLICATION

The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
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November 19 2009

Original Articles

Heat stress triggers apoptosis by impairing NF-kappaB survival signaling in malignant B cells

G Belardo, R Piva and M G Santoro

Leukemia advance online publication, November 19, 2009; doi:10.1038/leu.2009.227

Cathepsin B release after imatinib-mediated lysosomal membrane permeabilization triggers BCR–ABL cleavage and elimination of chronic myelogenous leukemia cells

A Puissant, P Colosetti, G Robert, J-P Cassuto, S Raynaud and P Auberger

Leukemia advance online publication, November 19, 2009; doi:10.1038/leu.2009.233

Diverging effects of HLA–DPB1 matching status on outcome following unrelated donor transplantation depending on disease stage and the degree of matching for other HLA alleles

B E Shaw, N P Mayor, N H Russell, J F Apperley, R E Clark, J Cornish, P Darbyshire, M E Ethell, J M Goldman, A-M Little, S Mackinnon, D I Marks, A Pagliuca, K Thomson, S G E Marsh and J A Madrigal

Leukemia advance online publication, November 19, 2009; doi:10.1038/leu.2009.239

Letter to the Editor

Optimized gene transfer into human primary leukemic T cell with NOD-SCID/leukemia-initiating cell activity

B Gerby, F Armstrong, P B de la Grange, H Medyouf, J Calvo, E Verhoeyen, F L Cosset, I Bernstein, S Amselem, N Boissel, H Dombret, T Leblanc, A Baruchel, J Landman-Parker, P Ballerini and F Pflumio

Leukemia advance online publication, November 19, 2009; doi:10.1038/leu.2009.235

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November 12 2009

Review

Mechanism of action of immunomodulatory drugs (IMiDS) in multiple myeloma

H Quach, D Ritchie, A K Stewart, P Neeson, S Harrison, M J Smyth and H M Prince

Leukemia advance online publication, November 12, 2009; doi:10.1038/leu.2009.236

Original Articles

DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4

M Bardini, R Spinelli, S Bungaro, E Mangano, L Corral, I Cifola, G Fazio, M Giordan, G Basso, G De Rossi, A Biondi, C Battaglia and G Cazzaniga

Leukemia advance online publication, November 12, 2009; doi:10.1038/leu.2009.203

Recruitment of PKC-betaII to lipid rafts mediates apoptosis-resistance in chronic lymphocytic leukemia expressing ZAP-70

C Meyer zum Büschenfelde, M Wagner, G Lutzny, M Oelsner, Y Feuerstacke, T Decker, C Bogner, C Peschel and I Ringshausen

Leukemia advance online publication, November 12, 2009; doi:10.1038/leu.2009.216

Letters to the Editor

A20 is targeted by promoter methylation, deletion and inactivating mutation in MALT lymphoma

E Chanudet, Y Huang, K Ichimura, G Dong, R A Hamoudi, J Radford, A C Wotherspoon, P G Isaacson, J Ferry and M-Q Du

Leukemia advance online publication, November 12, 2009; doi:10.1038/leu.2009.234

Activating mutation in the TSLPR gene in B-cell precursor lymphoblastic leukemia

E Chapiro, L Russell, E Lainey, S Kaltenbach, C Ragu, V Della-Valle, K Hanssens, E A Macintyre, I Radford-Weiss, E Delabesse, H Cavé, T Mercher, C J Harrison, F Nguyen-Khac, P Dubreuil and O A Bernard

Leukemia advance online publication, November 12, 2009; doi:10.1038/leu.2009.231

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November 5 2009

Meeting Report

The Eleventh International Childhood Acute Lymphoblastic Leukemia Workshop Report: Ponte di Legno, Italy, 6–7 May 2009

A Biondi, A Baruchel, S Hunger, G Masera, K Schmiegelow, M Schrappe and C H Pui

Leukemia advance online publication, November 5, 2009; doi:10.1038/leu.2009.211

Original Articles

Hsa-mir-125b-2 is highly expressed in childhood ETV6/RUNX1 (TEL/AML1) leukemias and confers survival advantage to growth inhibitory signals independent of p53

N Gefen, V Binder, M Zaliova, Y Linka, M Morrow, A Novosel, L Edry, L Hertzberg, N Shomron, O Williams, J Trka, A Borkhardt and S Izraeli

Leukemia advance online publication, November 5, 2009; doi:10.1038/leu.2009.208

WAVE1 regulates Bcl-2 localization and phosphorylation in leukemia cells

R Kang, D Tang, Y Yu, Z Wang, T Hu, H Wang and L Cao

Leukemia advance online publication, November 5, 2009; doi:10.1038/leu.2009.224

A comprehensive target selectivity survey of the BCR-ABL kinase inhibitor INNO-406 by kinase profiling and chemical proteomics in chronic myeloid leukemia cells

U Rix, L L Remsing Rix, A S Terker, N V Fernbach, O Hantschel, M Planyavsky, F P Breitwieser, H Herrmann, J Colinge, K L Bennett, M Augustin, J H Till, M C Heinrich, P Valent and G Superti-Furga

Leukemia advance online publication, November 5, 2009; doi:10.1038/leu.2009.228

TNF-alpha-converting enzyme (TACE/ADAM17)-dependent loss of CD30 induced by proteasome inhibition through reactive oxygen species

A M Vahdat, K S Reiners, V L Simhadri, D A Eichenauer, B Böll, A Chalaris, V R Simhadri, K Wiegmann, H-W Krell, S Rose-John, A Engert, E P von Strandmann and H P Hansen

Leukemia advance online publication, November 5, 2009; doi:10.1038/leu.2009.230

Letter to the Editor

Measuring the prognostic impact of ferritin levels in myelodysplastic syndrome patients: the role of susceptibility biases

A Jerez, A Fernández, M M Osma, V Roldán, F J Ortuño and V Vicente

Leukemia advance online publication, November 5, 2009; doi:10.1038/leu.2009.229

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October 29 2009

Spotlight Review

Targeted therapy in T-cell malignancies: dysregulation of the cellular signaling pathways

W-L Zhao

Leukemia advance online publication, October 29, 2009; doi:10.1038/leu.2009.223

Letters to the Editor

Mutual exclusion of ASXL1 and NPM1 mutations in a series of acute myeloid leukemias

N Carbuccia, V Trouplin, V Gelsi-Boyer, A Murati, J Rocquain, J Adélaïde, S Olschwang, L Xerri, N Vey, M Chaffanet, D Birnbaum and M J Mozziconacci

Leukemia advance online publication, October 29, 2009; doi:10.1038/leu.2009.218

Similar patterns of chromosome abnormalities in CML occur in addition to the Philadelphia chromosome with or without tyrosine kinase inhibitor treatment

C Haferlach, U Bacher, S Schnittger, T Weiss, W Kern and T Haferlach

Leukemia advance online publication, October 29, 2009; doi:10.1038/leu.2009.222

Myxoma virus targets primary human leukemic stem and progenitor cells while sparing normal hematopoietic stem and progenitor cells

M Kim, G J Madlambayan, M M Rahman, S E Smallwood, A M Meacham, K Hosaka, E W Scott, C R Cogle and G McFadden

Leukemia advance online publication, October 29, 2009; doi:10.1038/leu.2009.219

PML–RARalpha ligand-binding domain deletion mutations associated with reduced disease control and outcome after first relapse of APL

E Schachter-Tokarz, C Kelaidi, B Cassinat, C Chomienne, C Gardin, E Raffoux, H Dombret, P Fenaux and R Gallagher

Leukemia advance online publication, October 29, 2009; doi:10.1038/leu.2009.220

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October 22 2009

Original Articles

The JAK2 46/1 haplotype confers susceptibility to essential thrombocythemia regardless of JAK2V617F mutational status—clinical correlates in a study of 226 consecutive patients

A Pardanani, T L Lasho, C M Finke, N Gangat, A P Wolanskyj, C A Hanson and A Tefferi

Leukemia advance online publication, October 22, 2009; doi:10.1038/leu.2009.226

Involvement of RhoH GTPase in the development of B-cell chronic lymphocytic leukemia

A Sanchez-Aguilera, I Rattmann, D Z Drew, L U W Müller, V Summey, D M Lucas, J C Byrd, C M Croce, Y Gu, J A Cancelas, P Johnston, T Moritz and D A Williams

Leukemia advance online publication, October 22, 2009; doi:10.1038/leu.2009.217

JAK2 germline genetic variation affects disease susceptibility in primary myelofibrosis regardless of V617F mutational status: nullizygosity for the JAK2 46/1 haplotype is associated with inferior survival

A Tefferi, T L Lasho, M M Patnaik, C M Finke, K Hussein, W J Hogan, M A Elliott, M R Litzow, C A Hanson and A Pardanani

Leukemia advance online publication, October 22, 2009; doi:10.1038/leu.2009.225

Letters to the Editor

Aberrant telomere structure is characteristic of resistant chronic lymphocytic leukaemia cells

T Brugat, N Gault, I Baccelli, J Maës, A Roborel de Climens, F Nguyen-Khac, F Davi, H Merle-Béral, E Gilson, M Goodhardt and J Delic

Leukemia advance online publication, October 22, 2009; doi:10.1038/leu.2009.213

Influence of NPM1 and FLT3-ITD status on outcome in relapsed/refractory AML patients receiving salvage therapy including gemtuzumab ozogamicin

P Chevallier, T Prebet, A Pigneux, M Hunault, J Delaunay, F Perry, L Lode, S Richebourg, O Blanchet, N Vey, N Ifrah, N Milpied, D Blaise, J-L Harousseau and M Mohty

Leukemia advance online publication, October 22, 2009; doi:10.1038/leu.2009.214

Wilms tumor 1 (WT1) gene mutations in pediatric T-cell malignancies

A Renneville, S Kaltenbach, E Clappier, S Collette, J-B Micol, B Nelken, P Lepelley, N Dastugue, Y Benoît, Y Bertrand, C Preudhomme and H Cavé

Leukemia advance online publication, October 22, 2009; doi:10.1038/leu.2009.221

The expression levels of the pro-apoptotic XAF-1 gene modulate the cytotoxic response to Nutlin-3 in B chronic lymphocytic leukemia

P Secchiero, M G di Iasio, E Melloni, R Voltan, C Celeghini, M Tiribelli, M Dal Bo, V Gattei and G Zauli

Leukemia advance online publication, October 22, 2009; doi:10.1038/leu.2009.215

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October 15 2009

Original Articles

Selective FLT3 inhibitor FI-700 neutralizes Mcl-1 and enhances p53-mediated apoptosis in AML cells with activating mutations of FLT3 through Mcl-1/Noxa axis

K Kojima, M Konopleva, T Tsao, M Andreeff, H Ishida, Y Shiotsu, L Jin, Y Tabe and H Nakakuma

Leukemia advance online publication, October 15, 2009; doi:10.1038/leu.2009.212

Single-cell analysis reveals oligoclonality among 'low-count' monoclonal B-cell lymphocytosis

M C Lanasa, S D Allgood, A D Volkheimer, J P Gockerman, J F Whitesides, B K Goodman, J O Moore, J B Weinberg and M C Levesque

Leukemia advance online publication, October 15, 2009; doi:10.1038/leu.2009.192

Letters to the Editor

Novel RUNX1 mutations in familial platelet disorder with enhanced risk for acute myeloid leukemia: clues for improved identification of the FPD/AML syndrome

M C J Jongmans, R P Kuiper, C L Carmichael, E J Wilkins, N Dors, A Carmagnac, A Y N Schouten-van Meeteren, X Li, M Stankovic, E Kamping, H Bengtsson, E F P M Schoenmakers, A Geurts van Kessel, P M Hoogerbrugge, C N Hahn, P P Brons, H S Scott and N Hoogerbrugge

Leukemia advance online publication, October 15, 2009; doi:10.1038/leu.2009.210

Negative prognostic impact of PTEN mutation in pediatric T-cell acute lymphoblastic leukemia

P Y Jotta, M A Ganazza, A Silva, M B Viana, M J da Silva, L J G Zambaldi, J T Barata, S R Brandalise and J A Yunes

Leukemia advance online publication, October 15, 2009; doi:10.1038/leu.2009.209

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October 8 2009

Original Article

The synergy of panobinostat plus doxorubicin in acute myeloid leukemia suggests a role for HDAC inhibitors in the control of DNA repair

P Maiso, E Colado, E M Ocio, M Garayoa, J Martín, P Atadja, A Pandiella and J F San-Miguel

Leukemia advance online publication, October 8, 2009; doi:10.1038/leu.2009.182

Letter to the Editor

Oral fludarabine in untreated patients with B-cell chronic lymphocytic leukemia

C Shustik, A R Turner, P Desjardins, L Fernandez, S Rubin, L Larratt, A M V Duncan, D Rizi, A Sadura, L Shepherd, D Li, L Rassenti and T Kipps

Leukemia advance online publication, October 8, 2009; doi:10.1038/leu.2009.205

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October 1 2009

Spotlight Reviews

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review FREE

R Fonseca, P L Bergsagel, J Drach, J Shaughnessy, N Gutierrez, K Stewart, G Morgan, B Van Ness, M Chesi, S Minvielle, A Neri, B Barlogie, W M Kuehl, P Liebisch, F Davies, S Chen-Kiang, B G M Durie, R Carrasco, Orhan Sezer, Tony Reiman, Linda Pilarski and H Avet-Loiseau

Leukemia advance online publication, October 1, 2009; doi:10.1038/leu.2009.174

Choosing the best treatment strategy for chronic myeloid leukemia patients resistant to imatinib: weighing the efficacy and safety of individual drugs with BCR-ABL mutations and patient history FREE

E Jabbour, A Hochhaus, J Cortes, P La Rosée and H M Kantarjian

Leukemia advance online publication, October 1, 2009; doi:10.1038/leu.2009.193

Original Articles

In vivo dynamics of human cord blood-derived CD34- SCID-repopulating cells using intra-bone marrow injection

T Kimura, Y Matsuoka, M Murakami, T Kimura, M Takahashi, T Nakamoto, K Yasuda, K Matsui, K Kobayashi, S Imai, H Asano, R Nakatsuka, Y Uemura, Y Sasaki and Y Sonoda

Leukemia advance online publication, October 1, 2009; doi:10.1038/leu.2009.206

Oligomerization inhibition, combined with allosteric inhibition, abrogates the transformation potential of T315I-positive BCR/ABL

A A Mian, C Oancea, Z Zhao, O G Ottmann and M Ruthardt

Leukemia advance online publication, October 1, 2009; doi:10.1038/leu.2009.194

Stem cell traits in long-term co-culture revealed by time-lapse imaging

Y Song, A Bahnson, N Hall, H Yu, H Shen, D Koebler, R Houck, Y Xie and T Cheng

Leukemia advance online publication, October 1, 2009; doi:10.1038/leu.2009.191

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September 24 2009

Original Articles

EVI-1 interacts with histone methyltransferases SUV39H1 and G9a for transcriptional repression and bone marrow immortalization

S Goyama, E Nitta, T Yoshino, S Kako, N Watanabe-Okochi, M Shimabe, Y Imai, K Takahashi and M Kurokawa

Leukemia advance online publication, September 24, 2009; doi:10.1038/leu.2009.202

Analysis of factors that affect in vitro chemosensitivity of leukaemic stem and progenitor cells to gemtuzumab ozogamicin (Mylotarg) in acute myeloid leukaemia

M Jawad, C Seedhouse, U Mony, M Grundy, N H Russell and M Pallis

Leukemia advance online publication, September 24, 2009; doi:10.1038/leu.2009.199

Letters to the Editor

PTPN11 mutations in childhood acute lymphoblastic leukemia occur as a secondary event associated with high hyperdiploidy

C G Molteni, G te Kronnie, S Bicciato, T Villa, M Tartaglia, G Basso, A Biondi and G Cazzaniga

Leukemia advance online publication, September 24, 2009; doi:10.1038/leu.2009.200

Low or undetectable numbers of Philadelphia chromosome-positive leukemic stem cells (Ph+CD34+CD38neg) in chronic myeloid leukemia patients in complete cytogenetic remission after tyrosine kinase inhibitor therapy

S Mustjoki, P Rohon, K Rapakko, S Jalkanen, P Koskenvesa, T Lundán and K Porkka

Leukemia advance online publication, September 24, 2009; doi:10.1038/leu.2009.190

Successful treatment of molecular relapse in NPM1-positive AML using 5-azacytidine

M Wermke, C Thiede, A Kiani, G Ehninger, M Bornhäuser and U Platzbecker

Leukemia advance online publication, September 24, 2009; doi:10.1038/leu.2009.204

Inhibition of Syk protein tyrosine kinase induces apoptosis and blocks proliferation in T-cell non-Hodgkin's lymphoma cell lines

R A Wilcox, D X Sun, A Novak, A Dogan, S M Ansell and A L Feldman

Leukemia advance online publication, September 24, 2009; doi:10.1038/leu.2009.198

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September 17 2009

Original Articles

A different ontogenesis for chronic lymphocytic leukemia cases carrying stereotyped antigen receptors: molecular and computational evidence

N Darzentas, A Hadzidimitriou, F Murray, K Hatzi, P Josefsson, N Laoutaris, C Moreno, A Anagnostopoulos, J Jurlander, A Tsaftaris, N Chiorazzi, C Belessi, P Ghia, R Rosenquist, F Davi and K Stamatopoulos

Leukemia advance online publication, September 17, 2009; doi:10.1038/leu.2009.186

Different isoforms of the B-cell mutator activation-induced cytidine deaminase are aberrantly expressed in BCR–ABL1-positive acute lymphoblastic leukemia patients

I Iacobucci, A Lonetti, F Messa, A Ferrari, D Cilloni, S Soverini, F Paoloni, F Arruga, E Ottaviani, S Chiaretti, M Messina, M Vignetti, C Papayannidis, A Vitale, F Pane, P P Piccaluga, S Paolini, G Berton, A Baruzzi, G Saglio, M Baccarani, R Foà and G Martinelli

Leukemia advance online publication, September 17, 2009; doi:10.1038/leu.2009.197

Letters to the Editor

The function of the pleckstrin homology domain in BCR–ABL-mediated leukemogenesis

S Demehri, T O'Hare, C A Eide, C A Smith, J W Tyner, B J Druker and M W N Deininger

Leukemia advance online publication, September 17, 2009; doi:10.1038/leu.2009.196

TP53 mutations in myeloid malignancies are either homozygous or hemizygous due to copy number-neutral loss of heterozygosity or deletion of 17p

M Jasek, L P Gondek, N Bejanyan, R Tiu, J Huh, K S Theil, C O'Keefe, M A McDevitt and J P Maciejewski

Leukemia advance online publication, September 17, 2009; doi:10.1038/leu.2009.189

Extensive mutational status of genes and clinical outcome in pediatric acute myeloid leukemia

H Lapillonne, L Llopis, A Auvrignon, A Renneville, M Labopin, F Mazingue, C Perot, J-L Lai, N Philippe, P Ballerini, V Zurawski, M Adam, L Douay, G Leverger, J Landman-Parker and C Preudhomme

Leukemia advance online publication, September 17, 2009; doi:10.1038/leu.2009.172

A phase I/II trial of TLR-7 agonist immunotherapy in chronic lymphocytic leukemia

D E Spaner, Y Shi, D White, S Shaha, L He, A Masellis, K Wong and R Gorczynski

Leukemia advance online publication, September 17, 2009; doi:10.1038/leu.2009.195

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September 10 2009

Spotlight Review

The use of novel agents in the treatment of relapsed and refractory multiple myeloma FREE

J P Laubach, A Mahindra, C S Mitsiades, R L Schlossman, N C Munshi, I M Ghobrial, N Carreau, T Hideshima, K C Anderson and P G Richardson

Leukemia advance online publication, September 10, 2009; doi:10.1038/leu.2009.179

Original Articles

The therapeutic potential of p53 reactivation by nutlin-3a in ALK+ anaplastic large cell lymphoma with wild-type or mutated p53

E Drakos, V Atsaves, E Schlette, J Li, I Papanastasi, G Z Rassidakis and L J Medeiros

Leukemia advance online publication, September 10, 2009; doi:10.1038/leu.2009.180

A multi-center phase I study of clofarabine, etoposide and cyclophosphamide in combination in pediatric patients with refractory or relapsed acute leukemia

N Hijiya, P Gaynon, E Barry, L Silverman, B Thomson, R Chu, T Cooper, R Kadota, M Rytting, P Steinherz, V Shen, S Jeha, R Abichandani and W L Carroll

Leukemia advance online publication, September 10, 2009; doi:10.1038/leu.2009.185

High dose ara-C in the treatment of newly diagnosed acute promyelocytic leukemia: long-term results of the German AMLCG

E Lengfelder, C Haferlach, S Saussele, T Haferlach, B Schultheis, S Schnittger, W-D Ludwig, P Staib, C Aul, A Grüneisen, W Kern, A Reichle, H Serve, W E Berdel, J Braess, K Spiekermann, B Wörmann, M-C Sauerland, A Heinecke, W Hiddemann, R Hehlmann and T Büchner for the German AML Cooperative Group (AMLCG)

Leukemia advance online publication, September 10, 2009; doi:10.1038/leu.2009.183

Adult acute erythroleukemia: an analysis of 91 patients treated at a single institution

F P S Santos, S Faderl, G Garcia-Manero, C Koller, M Beran, S O'Brien, S Pierce, E J Freireich, X Huang, G Borthakur, C Bueso-Ramos, M de Lima, M Keating, J Cortes, H Kantarjian and F Ravandi

Leukemia advance online publication, September 10, 2009; doi:10.1038/leu.2009.181

Letters to the Editor

Large but not small copy-number alterations correlate to high-risk genomic aberrations and survival in chronic lymphocytic leukemia: a high-resolution genomic screening of newly diagnosed patients

R Gunnarsson, A Isaksson, M Mansouri, H Göransson, M Jansson, N Cahill, M Rasmussen, J Staaf, J Lundin, S Norin, A M Buhl, K E Smedby, H Hjalgrim, K Karlsson, J Jurlander, G Juliusson and R Rosenquist

Leukemia advance online publication, September 10, 2009; doi:10.1038/leu.2009.187

Identification of native, immunogenic peptides from Cyclin D1

M S von Bergwelt-Baildon, A Shimabukuro-Vornhagen, C M Wendtner and E Kondo

Leukemia advance online publication, September 10, 2009; doi:10.1038/leu.2009.184

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September 3 2009

Review

Contribution of bone microenvironment to leukemogenesis and leukemia progression

F Ayala, R Dewar, M Kieran and R Kalluri

Leukemia advance online publication, September 3, 2009; doi:10.1038/leu.2009.175

Letter to the Editor

Cranial irradiation does not result in pituitary–gonadal axis dysfunction in very long-term male survivors of childhood acute lymphoblastic leukemia

N J van Casteren, R Pieters, G R Dohle, M van Baalen, S Neggers and M M van den Heuvel-Eibrink

Leukemia advance online publication, September 3, 2009; doi:10.1038/leu.2009.165

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August 27 2009

Leading Article

Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation

R Ono, H Kumagai, H Nakajima, A Hishiya, T Taki, K Horikawa, K Takatsu, T Satoh, Y Hayashi, T Kitamura and T Nosaka

Leukemia advance online publication, August 27, 2009; doi:10.1038/leu.2009.177

Original Article

Antileukemic activity of valproic acid in chronic lymphocytic leukemia B cells defined by microarray analysis

B Stamatopoulos, N Meuleman, C De Bruyn, P Mineur, P Martiat, D Bron and L Lagneaux

Leukemia advance online publication, August 27, 2009; doi:10.1038/leu.2009.176

Letters to the Editor

Analyses of TET2 mutations in post-myeloproliferative neoplasm acute myeloid leukemias

L Couronné, E Lippert, J Andrieux, O Kosmider, I Radford-Weiss, D Penther, N Dastugue, F Mugneret, M Lafage, N Gachard, N Nadal, O A Bernard and F Nguyen-Khac on behalf of the Groupe Francophone de Cytogénétique Hématologique

Leukemia advance online publication, August 27, 2009; doi:10.1038/leu.2009.169

Characterizing chromosomal break points of t(12;21)[ETV6–RUNX1]-positive leukaemia using multiple tiling PCR on whole-genome-amplified DNA

U Lausten-Thomsen, H O Madsen and K Schmiegelow

Leukemia advance online publication, August 27, 2009; doi:10.1038/leu.2009.170

Identification of a novel TEL–Lyn fusion gene in primary myelofibrosis

H Tanaka, M Takeuchi, Y Takeda, S Sakai, D Abe, C Ohwada, E Sakaida, N Shimizu, Y Saito, S Miyagi, A Iwama and C Nakaseko

Leukemia advance online publication, August 27, 2009; doi:10.1038/leu.2009.167

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August 13 2009

Letter to the Editor

Multitargeted tyrosine kinase inhibitor stimulates expression of IL-6 and activates JAK2/STAT5 signaling in acute myelogenous leukemia cells

C Nishioka, T Ikezoe, J Yang and A Yokoyama

Leukemia advance online publication, August 13, 2009; doi:10.1038/leu.2009.163

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August 6 2009

Letters to the Editor

Allergy and the risk of childhood leukemia: a meta-analysis

S Dahl, L S Schmidt, T Vestergaard, J Schüz and K Schmiegelow

Leukemia advance online publication, August 6, 2009; doi:10.1038/leu.2009.162

BCR/ABL kinase interacts with and phosphorylates the RAD51 paralog, RAD51B

A Slupianek, S K Jozwiakowski, E Gurdek and T Skorski

Leukemia advance online publication, August 6, 2009; doi:10.1038/leu.2009.164

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