TABLE OF CONTENTS
Volume 20, Issue 7 (July 2006)
Review
Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia
F Weerkamp, J J M van Dongen and F J T Staal
Leukemia 20: 1197-1205; advance online publication, May 11, 2006; doi:10.1038/sj.leu.2404255
Editorial
Is the risk of acute lymphoblastic leukemia reduced in siblings to children with the disease? A novel hypothesis explored by international collaboration
K Schmiegelow and H Hjalgrim
Leukemia 20: 1206-1208; doi:10.1038/sj.leu.2404250
Commentary
Aristotle: the first student of angiogenesis
E Crivellato and D Ribatti
Leukemia 20: 1209-1210; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404256
Original Articles
Acute Leukemias
Expression of 
-catenin by acute myeloid leukemia cells predicts enhanced clonogenic capacities and poor prognosis
L Ysebaert, G Chicanne, C Demur, F De Toni, N Prade-Houdellier, J-B Ruidavets, V Mansat-De Mas, F Rigal-Huguet, G Laurent, B Payrastre, S Manenti and C Racaud-Sultan
Leukemia 20: 1211-1216; advance online publication, May 11, 2006; doi:10.1038/sj.leu.2404239
Stability and prognostic influence of FLT3 mutations in paired initial and relapsed AML samples
J Cloos, B F Goemans, C J Hess, J W van Oostveen, Q Waisfisz, S Corthals, D de Lange, N Boeckx, K Hählen, D Reinhardt, U Creutzig, G J Schuurhuis, Ch M Zwaan and G J L Kaspers
Leukemia 20: 1217-1220; advance online publication, April 27, 2006; doi:10.1038/sj.leu.2404246
Chronic Lymphocytic Leukemias
A new automated flow cytometry data analysis approach for the diagnostic screening of neoplastic B-cell disorders in peripheral blood samples with absolute lymphocytosis
E S Costa, M E Arroyo, C E Pedreira, M A García-Marcos, M D Tabernero, J Almeida and A Orfao
Leukemia 20: 1221-1230; advance online publication, May 25, 2006; doi:10.1038/sj.leu.2404241
IgVH genes mutation and usage, ZAP-70 and CD38 expression provide new insights on B-cell prolymphocytic leukemia (B-PLL)
I Del Giudice, Z Davis, E Matutes, N Osuji, N Parry-Jones, A Morilla, V Brito-Babapulle, D Oscier and D Catovsky
Leukemia 20: 1231-1237; advance online publication, April 27, 2006; doi:10.1038/sj.leu.2404238
Cytogenetics and Molecular Genetics
Molecular cytogenetic study of 126 unselected T-ALL cases reveals high incidence of TCR locus rearrangements and putative new T-cell oncogenes
B Cauwelier, N Dastugue, J Cools, B Poppe, C Herens, A De Paepe, A Hagemeijer and F Speleman
Leukemia 20: 1238-1244; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404243
A new recurrent 9q34 duplication in pediatric T-cell acute lymphoblastic leukemia FREE
P van Vlierberghe, J P P Meijerink, C Lee, A A Ferrando, A T Look, E R van Wering, H B Beverloo, J C Aster and R Pieters
Leukemia 20: 1245-1253; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404247
Signal Transduction and Cytokines
Synergy between an IGF-1R antibody and Raf/MEK/ERK and PI3K/Akt/mTOR pathway inhibitors in suppressing IGF-1R-mediated growth in hematopoietic cells
F E Bertrand, L S Steelman, W H Chappell, S L Abrams, J G Shelton, E R White, D L Ludwig and J A McCubrey
Leukemia 20: 1254-1260; advance online publication, April 27, 2006; doi:10.1038/sj.leu.2404217
Transcriptional Control and Deregulation
MTB, the murine homolog of condensin II subunit CAP-G2, represses transcription and promotes erythroid cell differentiation
Y Xu, C G Leung, D C Lee, B K Kennedy and J D Crispino
Leukemia 20: 1261-1269; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404252
Apoptosis
Human telomerase reverse transcriptase protects hematopoietic progenitor TF-1 cells from death and quiescence induced by cytokine withdrawal FREE
S Li, M J Ferguson, C J Hawkins, C Smith and N J Elwood
Leukemia 20: 1270-1278; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404251
Lymphoma
CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to 
-secretase inhibitors
T Palomero, K C Barnes, P J Real, J L Glade Bender, M L Sulis, V V Murty, A I Colovai, M Balbin and A A Ferrando
Leukemia 20: 1279-1287; advance online publication, May 11, 2006; doi:10.1038/sj.leu.2404258
Letters to the Editor
Prognostic value of Cyclin D2 mRNA expression in newly diagnosed multiple myeloma treated with high-dose chemotherapy and tandem autologous stem cell transplantations
I Hanamura, Y Huang, F Zhan, B Barlogie and J Shaughnessy Jr
Leukemia 20: 1288-1290; advance online publication, May 11, 2006; doi:10.1038/sj.leu.2404253
Hypoxia suppresses BCR/Abl and selects imatinib-insensitive progenitors within clonal CML populations
S Giuntoli, E Rovida, V Barbetti, M G Cipolleschi, M Olivotto and P Dello Sbarba
Leukemia 20: 1291-1293; advance online publication, May 18, 2006; doi:10.1038/sj.leu.2404224
A novel TEL-AML1 fusion transcript involving the pro-apoptotic gene BCL-G in pediatric precursor B acute lymphoblastic leukemia
M Abdelhaleem, Q Yi, K Beimnet and J Hitzler
Leukemia 20: 1294; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404249
A retrospective study of 69 patients with t(6;9)(p23;q34) AML emphasizes the need for a prospective, multicenter initiative for rare 'poor prognosis' myeloid malignancies
M L Slovak, H Gundacker, C D Bloomfield, G Dewald, F R Appelbaum, R A Larson, M S Tallman, J M Bennett, D L Stirewalt, S Meshinchi, C L Willman, Y Ravindranath, T A Alonzo, A J Carroll, S C Raimondi and N A Heerema
Leukemia 20: 1295-1297; advance online publication, April 20, 2006; doi:10.1038/sj.leu.2404233
Reply to Kremer M et al., The JAK2 V617F mutation occurs frequently in myelodysplastic/myeloproliferative diseases, but is absent in true myelodysplastic syndromes with fibrosis
K Ohyashiki and J H Ohyashiki
Leukemia 20: 1297-1298; advance online publication, April 13, 2006; doi:10.1038/sj.leu.2404232
Chromosomal aberrations in leukaemia cells may delete tumour target antigens of stem cell-based immunotherapy
L Hambach, B A Nijmeijer, J J M Drabbels, J H F Falkenburg and Els Goulmy
Leukemia 20: 1298-1300; advance online publication, April 20, 2006; doi:10.1038/sj.leu.2404237
Genetic rearrangement of FOXP1 is predominantly detected in a subset of diffuse large B-cell lymphomas with extranodal presentation
E Haralambieva, P Adam, R Ventura, T Katzenberger, J Kalla, S Höller, M Hartmann, A Rosenwald, A Greiner, H K M
ller-Hermelink, A H Banham and G Ott
Leukemia 20: 1300-1303; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404244
Methylation analysis of asparagine synthetase gene in acute lymphoblastic leukemia cells
T Akagi, D Yin, N Kawamata, C R Bartram, W-K Hofmann, I Wolf, C W Miller and H P Koeffler
Leukemia 20: 1303-1306; advance online publication, April 6, 2006; doi:10.1038/sj.leu.2404216
G1 cell-cycle arrest and apoptosis by histone deacetylase inhibition in MLL-AF9 acute myeloid leukemia cells is p21 dependent and MLL-AF9 independent
R Tonelli, R Sartini, R Fronza, F Freccero, M Franzoni, D Dongiovanni, M Ballarini, S Ferrari, M D'apolito, G Di Cola, G Capranico, A Khobta, R Campanini, P Paolucci, S Minucci and A Pession
Leukemia 20: 1307-1310; advance online publication, April 13, 2006; doi:10.1038/sj.leu.2404221
ArgBP2, encoding a negative regulator of ABL, is fused to MLL in a case of infant M5 acute myeloid leukemia involving 4q35 and 11q23
A Pession, L Lo Nigro, L Montemurro, S Serravalle, R Fazzina, G Izzi, G Nucifora, R Slany and R Tonelli
Leukemia 20: 1310-1313; advance online publication, April 20, 2006; doi:10.1038/sj.leu.2404222
BAFF and APRIL as osteoclast-derived survival factors for myeloma cells: a rationale for TACI-Fc treatment in patients with multiple myeloma
M Abe, S Kido, M Hiasa, A Nakano, A Oda, H Amou and T Matsumoto
Leukemia 20: 1313-1315; advance online publication, April 13, 2006; doi:10.1038/sj.leu.2404228
The JAK2 V617F mutation occurs frequently in myelodysplastic/myeloproliferative diseases, but is absent in true myelodysplastic syndromes with fibrosis
M Kremer, T Horn, T Dechow, A Tzankov, L Quintanilla-Martínez and F Fend
Leukemia 20: 1315-1316; advance online publication, April 13, 2006; doi:10.1038/sj.leu.2404231
Bcl2 phosphorylation and active PKC 
are associated with poor survival in AML
S Kurinna, M Konopleva, S L Palla, W Chen, S Kornblau, R Contractor, X Deng, W S May, M Andreeff and P P Ruvolo
Leukemia 20: 1316-1319; advance online publication, April 27, 2006; doi:10.1038/sj.leu.2404248
The JAK2 V617F mutation identifies a subgroup of MDS patients with isolated deletion 5q and a proliferative bone marrow
W Ingram, N C Lea, J Cervera, U Germing, P Fenaux, B Cassinat, J J Kiladjian, J Varkonyi, P Antunovic, N B Westwood, M J Arno, A Mohamedali, J Gaken, T Kontou, B H Czepulkowski, N A Twine, J Tamaska, J Csomer, S Benedek, N Gattermann, E Zipperer, A Giagounidis, Z Garcia-Casado, G Sanz and G J Mufti
Leukemia 20: 1319-1321; advance online publication, April 13, 2006; doi:10.1038/sj.leu.2404215
Immunophenotypic identification of acute myeloid leukemia with monocytic differentiation
Y Xu, R W McKenna, K S Wilson, N J Karandikar, R A Schultz and S H Kroft
Leukemia 20: 1321-1324; advance online publication, April 27, 2006; doi:10.1038/sj.leu.2404242
Presence of JAK2 V617F tyrosine kinase mutation as a myeloid-lineage-specific mutation in chronic neutrophilic leukaemia
N C Lea, Z Lim, N B Westwood, M J Arno, J Gäken, A Mohamedali and G J Mufti
Leukemia 20: 1324-1326; advance online publication, May 4, 2006; doi:10.1038/sj.leu.2404240
Promoter hypermethylation silences expression of the HoxA4 gene and correlates with IgVh mutational status in CLL
G Strathdee, A Sim, A Parker, D Oscier and R Brown
Leukemia 20: 1326-1329; advance online publication, May 11, 2006; doi:10.1038/sj.leu.2404254
