Volume 93 Issue 3, March 2013
A conditionally replicating adenovirus armed with osteoprotegerin, an inhibitor of osteoclastogenesis, inhibits the progression of bone metastases of prostate cancer in vivo. The cover shows images generated by microcomputed tomography of the proximal tibiae of naïve SCID mice and mice with intratibial tumors that were treated with controls or the armed adenovirus. For more information, see the paper by Cody et al on page 268, this issue.
