See what scientists world-wide have been citing, reading and sharing. In this Web Collection we highlight a selection of articles from 2018 and 2019 which top the list of the journal's most cited, most read and most shared (including press coverage, blogs and Twitter). They showcase the breadth of scope and coverage that the Journal of Human Hypertension consistently delivers to its readers

The 2019 Nobel Prize in Physiology or Medicine was jointly awarded to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza “for their discoveries of how cells sense and adapt to oxygen availability”. Collectively, their research led to an understanding of the elegant mechanism cells use to respond to changes in oxygen levels, a fundamental process that underpins normal physiologic functioning and plays a critical role in several diseases, including cancer. Via a combination of oxygen-dependant targeted destruction of the Hypoxia Inducible Factor and modulation of gene expression, cells are equipped to survive in a fluctuating environment. This pioneering research helped pave the way towards a plethora of medications that target this pathway. In celebration of their success, we have featured some of their articles in this collection, which includes content from Oncogene, British Journal of Cancer, Pediatric Research, Gene Therapy, Cell Death and Disease, and the Journal of Human Hypertension.

Read the abstracts from the 2019 Annual Scientific Meeting of the British and Irish Hypertension Society (BIHS) held in the Edgbaston Park Hotel and Conference Centre, Birmingham, 16 - 18 September 2019.

To coincide with the British and Irish Hypertension Society's Annual Meeting, which will be taking place from 16th - 18th September in Birmingham, the Editors of the Journal of Human Hypertension have pulled together a collection of articles, which focus on the theme of cardiovascular risk. We hope that this collection of articles will add to an in depth discussion of the topic and the field of hypertension as a whole and may provide some arguments to fuel the discussion further. Papers are free to view for 6 weeks.

In this special issue the Journal of Human Hypertension hope to focus attention of the emerging problem of hypertension in the subcontinent. We hope it will raise awareness of the magnitude of the problem, the various obstacles involved in the implementation and delivery of healthcare and help to provide some solution to these issues.

The European Society of Hypertension's 29th Annual Meeting on Hypertension and Cardiovascular Protection is upon us, 21st - 24th June. The European Society of Hypertension (ESH) is developing an outstanding scientific programme, that will include multiple State-of-the-Art Lectures, Debates and Round Tables on issues on major current interest and controversy. The Editors of the Journal of Human Hypertension, in the spirit of this important event, are pleased to showcase the work of researchers in the field on Diabetes and Hypertension, a topic they feel is critical in the field at this time.

See what scientists world-wide have been citing, reading and sharing. In this Web Collection we highlight a selection of articles from 2017 and 2018 which top the list of the journal's most cited, most read and most shared (including press coverage, blogs and Twitter). They showcase the breadth of scope and coverage that the Journal of Human Hypertension consistently delivers to its readers.

Non-adherence to antihypertensive medications is very common among the hypertensive community and an important contributor to the phenomenon of apparent resistance to treatment. This group of articles focuses on its prevalence, determinants, detection and suggested approaches to management.

Arterial stiffness has long been known to predict development of cardiovascular events and is a major determinant of central blood pressure, which prognosticates for cardiovascular outcomes independently of, and possibly with greater predictive power than, brachial blood pressure. This collection of articles focuses in new findings related to the measurement of these parameters and their association with a variety of endpoints in different ethnic groups.

This article collection focuses on mineralocorticoids in human hypertension. Mineralocorticoids’ importance in blood pressure regulation is highlighted by altered mineralocorticoid activity--or simulacra of altered mineralocorticoid activity--in monogenic disorders of hypertension. Primary aldosteronism is the most common form of secondary hypertension and this condition of inappropriate mineralocorticoid secretion is present in approximately 20% of patients with resistant hypertension.

The Academic Journal portfolio recently published a Precision Medicine campaign, in which our Editors selected over 50 articles across a range of specialities which they believe contribute to the advancement of research in this area. In light of this the Journal of Human Hypertension is pleased to showcase more research that the journal has published on this increasingly interesting and evolving field of medicine, the potential of which can transform the care and treatment of individuals globally.