Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
This special issue reflects the intersection between molecular cytogenetics and comparative genomics and emphasizes their use to confirm and refine syntenies, identify breakpoints, neocentromeres and other chromosomal features that are responsible for the myriad of karyotypes that characterize biological lineages. It features papers that discuss chromosomal diversification at different phylogenetic levels and presents new and exciting insights to some of the molecular mechanisms that are thought to underpin the structural modification of karyotypes (including the evolution of sex chromosomes and dosage compensation in amniotes), and new technologies that may impact on the precision by which we identify and characterize chromosomal rearrangements in future.
