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  • Special |

    Epigenetic processes, which do not change the sequence of the DNA itself, are known to modify the way genes are expressed during development. They include DNA methylation, histone modifications and RNA interference, all processes that are associated with changes in chromatin conformation. Recent research into the contribution of epigenetics to the differential regulation of gene expression, imprinting (where expression depends on the parent-of-origin), gene silencing, and the involvement of transposable elements in these processes, have all shed fresh light on the relationships between genotype and phenotype. These processes could lead to the onset of diseases in adulthood, including some tumours. In this special issue, we provide a selection of reviews that covers epigenetic processes occurring at several different levels, and in various organisms.

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  • Special |

    Completion of the genome sequence for an organism can produce a phase change in our understanding of both its function, and its evolution. The information gained is multiplied when closely related species are sequenced in parallel. This special issue of Heredity contains a set of papers on the genetics of three closely related parasitoid wasps from the genus Nasonia. These papers are a first batch of genetic and population genetic analysis that have utilized these genome sequences, and tackle studies as diverse as recombination and neurotransmission, hybrid breakdown and host preference. They highlight the new research avenues available in this emerging genetic model organism

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  • Special |

    The origin of species is one of the most actively studied topics in evolutionary biology. This special issue of Heredity show the breadth of current studies into the genetics of speciation, a field currently absorbing the new possibilities of the post-genomic era. Understanding the genetics of speciation concerns trying to identify key changes underlying differentiation and reproductive isolation rather than those carried along in its wake. These papers address a broad range of organisms and present new and exciting insights. Loci of large effect are being identified and we are, at last, making progress in studying these in an ecological context and addressing the forms of natural or sexual selection responsible for their substitution.

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  • Special |

    This special issue features papers in evolutionary developmental biology - 'evo-devo' - that explore the roles of genetic variation in the evolution of developmental processes in animals. This collection of papers reflects the way in which the field has expanded to consider genetic variation in natural populations, and is doing so in the context of the evolution of morphologies that are relevant in an ecological arena, such as in interactions with competitors, with potential mating partners or with predators.

    Image: enot-poloskun