Clinical Study

Eye (2007) 21, 324–330. doi:10.1038/sj.eye.6702171; published online 11 November 2005

Age-related maculopathy and cataract surgery outcomes: visual acuity and health-related quality of life

Commercial relationship: None

T Q Pham1, S Cugati1, E Rochtchina1, P Mitchell1, A Maloof2 and J J Wang1

  1. 1Department of Ophthalmology (Centre for Vision Research, Westmead Millennium Institute), University of Sydney, Westmead Hospital, Westmead, NSW, Australia
  2. 2Department of Ophthalmology, Westmead Hospital, Westmead, NSW, Australia

Correspondence: JJ Wang, Centre for Vision Research, Department of Ophthalmology, University of Sydney, Westmead Hospital, Hawkesbury Rd, Westmead, NSW 2145, Australia. Tel: +61 2 9845 5006; Fax: +61 2 9845 8345; E-mail:

Received 3 August 2005; Revised 20 September 2005; Accepted 23 September 2005; Published online 11 November 2005.





To assess visual acuity (VA) and health-related quality of life (HRQoL) outcomes in patients with and without age-related maculopathy (ARM) after cataract surgery.



Patients aged 60+ years who had undergone cataract surgery at the Westmead Hospital during 2001–2003 were re-examined 1–3 years after surgery. Tests included VA and assessment of visual- and HRQoL using standardised questionnaires (VF-14, SF-12). Preoperative comorbidity data were collected from medical records. Poor surgical outcomes (VA<6/12; no VA improvement; lowest quintile of VF-14, SF-12 scores) were compared in patients with and without ARM, adjusting for age, sex, preoperative systemic comorbidities, ocular comorbidities and surgical or postoperative complications.



Of 622 surviving patients, 454 (73%) were followed up for a mean period of 2.8 years. Similar proportions with VAgreater than or equal to6/12 were observed in patients with (80.2%) and without (88.8%) pre-existing ARM. Preoperative early ARM was only associated with slightly lower mean VF-14 scores (87.64 with vs92.58 without ARM, P=0.01). Increasing age and preoperative ocular comorbidities were associated with all poor outcomes measured. Low SF-12 scores were associated with preoperative systemic comorbidities.



Our study documents favourable cataract surgical outcomes 1–3 years after cataract surgery in patients with preoperative ARM.


surgical outcomes, cataract surgery, age-related maculopathy, VF-14, health-related quality of life, SF-12