Abstract
Objectives:
To investigate whether a high consumption of red or processed meat is associated with increased risk of coronary heart disease (CHD).
Subjects/Methods:
The subjects were 517 men and 635 women, who were members of the Medical Research Council National Survey of Health and Development, 1946 birth cohort. Assessment of diet was carried out at two time points 1989 and 1999 with outcome measures collected in 1999. Food intake data were recorded in 5-day diaries. Meat consumption was estimated by adding individual meat portions to the meat fractions of composite dishes.
Results:
There was no significant association between red or processed meat consumption in 1989 and 1999 and serum cholesterol concentrations and blood pressure measured in 1999. The combined intake of red and processed meat in 1999 had a significant positive association with blood pressure in men only. Red and processed meat intakes in 1989, separately and combined, had a significant positive association with waist circumference in 1999: a 10 g increase in red meat consumption accounted for a 0.3 cm increase in waist circumference; P=0.04 (men), 0.05 (women).
Conclusions:
Consumption of red or processed meat assessed separately was not related to the major risk factors for CHD but contributed to increased waist circumference that has also been identified as a risk factor.
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References
Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM et al. (1997). A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med 336, 1117–1124.
Ascherio A, Hennekens C, Willett WC, Sacks F, Rosner B, Manson J et al. (1996). Prospective study of nutritional factors, blood pressure, and hypertension among US women. Hypertension 27, 1065–1072.
Beaglehole R, Magnus P (2002). The search for new risk factors for coronary heart disease: occupational therapy for epidemiologists? Int J Epidemiol 31, 1117–1122; author reply 1134–1135.
Beauchesne-Rondeau E, Gascon A, Bergeron J, Jacques H (2003). Plasma lipids and lipoproteins in hypercholesterolemic men fed a lipid-lowering diet containing lean beef, lean fish, or poultry. Am J Clin Nutr 77, 587–593.
British Heart Foundation 2007: www.heartstats.org.
Clarke R, Frost C, Collins R, Appleby P, Peto R (1997). Dietary lipids and blood cholesterol: quantitative meta-analysis of metabolic ward studies. BrMJ 314, 112–117.
Cosgrove M, Flynn A, Kiely M (2005a). Consumption of red meat, white meat and processed meat in Irish adults in relation to dietary quality. B J Nutr 93, 933–942.
Cosgrove M, Flynn A, Kiely M (2005b). Impact of disaggregation of composite foods on estimates of intakes of meat and meat products in Irish adults. Public Health Nutr 8, 327–337.
Department of Health (1994). Nutritional Aspects of Cardiovascular Disease. Report of the Cardiovascular Review Group Committee on Medical Aspects of Food Policy. HMSO: London.
Food Standards Agency (2002). McCance and Widdowson's The Composition of Foods, Sixth summary edition. Royal Society of Chemistry: Cambridge.
Gazi I, Tsimihodimos V, Filippatos TD, Saougos VG, Bairaktari ET, Tselepis AD et al. (2006). LDL cholesterol estimation in patients with the metabolic syndrome. Lipids Health Dis 5, 8–15.
German JB, Dillard CJ (2004). Saturated fats: what dietary intake? Am J Clin Nutr 80, 550–559.
Haveman-Nies A, Tucker KL, de Groot LC, Wilson PW, van Staveren WA (2001). Evaluation of dietary quality in relationship to nutritional and lifestyle factors in elderly people of the US Framingham Heart Study and the European SENECA study. Eur J Clin Nutr 55, 870–880.
Henderson L, Gregory J, Irving K (2003). The National Diet and Nutrition Survey: adults aged 19–64 years Volume 2. Energy, Protein, Carbohydrate, Fat and Alcohol Intake. The Stationery Office: London.
Hu FB, Rimm EB, Stampfer MJ, Ascherio A, Spiegelman D, Willett WC (2000). Prospective study of major dietary patterns and risk of coronary heart disease in men. Am J Clin Nutr 72, 912–921.
Hu FB, Stampfer MJ, Manson JE, Ascherio A, Colditz GA, Speizer FE et al. (1999). Dietary saturated fats and their food sources in relation to the risk of coronary heart disease in women. Am J Clin Nutr 70, 1001–1008.
Khaw KT, Bingham S, Welch A, Luben R, O’Brien E, Wareham N et al. (2004). Blood pressure and urinary sodium in men and women: the Norfolk Cohort of the European Prospective Investigation into Cancer (EPIC-Norfolk). Am J Clin Nutr 80, 1397–1403.
Krauss RM, Eckel RH, Howard B, Appel LJ, Daniels SR, Deckelbaum RJ et al. (2000). AHA Dietary Guidelines: revision 2000: A statement for healthcare professionals from the Nutrition Committee of the American Heart Association. Stroke 31, 2751–2766.
Kushi LH, Lenart EB, Willett WC (1995). Health implications of Mediterranean diets in light of contemporary knowledge. 2 Meat, wine, fats, and oils. Am J Clin Nutr 61, 1416S–1427S.
Law MR, Frost CD, Wald NJ (1991). Dietary salt and blood pressure. J Hypertens Suppl 9, S37–S41; discussion S47–S49.
Li D, Siriamornpun S, Wahlqvist ML, Mann NJ, Sinclair AJ (2005). Lean meat and heart health. Asia Pac J Clin Nutr 14, 113–119.
Linseisen J, Kesse E, Slimani N, Bueno-De-Mesquita HB, Ocke MC, Skeie G et al. (2002). Meat consumption in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohorts: results from 24-hour dietary recalls. Public Health Nutr 5, 1243–1258.
Miura K, Greenland P, Stamler J, Liu K, Daviglus ML, Nakagawa H (2004). Relation of vegetable, fruit, and meat intake to 7-year blood pressure change in middle-aged men: the Chicago Western Electric Study. Am J Epidemiol 591, 572–580.
Newby PK, Muller D, Hallfrisch J, Qiao N, Andres R, Tucker KL (2003). Dietary patterns and changes in body mass index and waist circumference in adults. Am J Clin Nutr 77, 1417–1425.
Nicklas TA, Farris RP, Myers L, Berenson GS (1995). Impact of meat consumption on nutritional quality and cardiovascular risk factors in young adults: the Bogalusa Heart Study. J Am Diet Assoc 95, 887–892.
Paul AA, Southgate DAT (1978). McCance and Widdowson's The Composition of Foods, 4th edn. HMSO: London.
Prynne CJ, Paul AA, Mishra GD, Greenberg DC, Wadsworth MEJ (2005). Changes in intake of key nutrients over 17 years during adult life of a British birth cohort. Br J Nutr 94, 368–376.
Prynne CJ, Wagemakers J, Stephen A, Wadsworth ME (2007). Meat consumption after disaggregation of meat dishes of a cohort of British adults in 1989 and 1999 and relation to diet quality. submitted.
Rosell M, Appleby P, Spencer E, Key T (2006). Weight gain over 5 years in 21 966 meat-eating, fish-eating, vegetarian, and vegan men and women in EPIC-Oxford. Int J Obes (Lond) 30, 1389–1396.
Sacks FM, Kass EH (1988). Low blood pressure in vegetarians: effects of specific foods and nutrients. Am J Clin Nutr 48, 795–800.
Safeer RS, Ugalat PS (2002). Cholesterol treatment guidelines update. Am Fam Phys 65, 871–880.
Scott LW, Dunn JK, Pownall HJ, Brauchi DJ, McMann MC, Herd JA et al. (1994). Effects of beef and chicken consumption on plasma lipid levels in hypercholesterolemic men. Arch Intern Med 154, 1261–1267.
Slattery ML, Jacobs Jr DR, Hilner JE, Caan BJ, Van Horn L, Bragg C et al. (1991). Meat consumption and its associations with other diet and health factors in young adults: the CARDIA study. Am J Clin Nutr 54, 930–935.
Steffen LM, Kroenke CH, Yu X, Pereira MA, Slattery ML, Van Horn L et al. (2005). Associations of plant food, dairy product, and meat intakes with 15-y incidence of elevated blood pressure in young black and white adults: the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Clin Nutr 82, 1169–1177.
Tang JL, Armitage JM, Lancaster T, Silagy CA, Fowler GH, Neil HA (1998). Systematic review of dietary intervention trials to lower blood total cholesterol in free-living subjects. Br Med J 316, 1213–1220.
Togo P, Osler M, Sorensen TI, Heitmann BL (2001). Food intake patterns and body mass index in observational studies. Int J Obes Relat Metab Disord 25, 1741–1751.
Ulbricht T, Southgate DAT (1991). Coronary heart disease: seven dietary factors. Lancet 338, 985–992.
Wadsworth ME, Butterworth SL, Hardy RJ, Kuh DJ, Richards M, Langenberg C et al. (2003). The life course prospective design: an example of benefits and problems associated with study longevity. Soc Sci Med 57, 2193–2205.
Wadsworth ME, Mann SL, Rodgers B, Kuh DJ, Hilder WS, Yusuf EJ (1992). Loss and representativeness in a 43 year follow up of a national birth cohort. J Epidemiol Commun Health 46, 300–304.
Acknowledgements
JW acknowledges the support she received from the Netherlands Heart Foundation for her internship in Cambridge. This work was supported by the UK Medical Research Council.
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Contributors: CJP and JJMFW were responsible for analysis of the data and preparation of the manuscript. AMS conceptualized the study and provided critical revision of the paper. MEJW was responsible for the cohort study design and data collection and approved the project and also provided critical revision of the paper.
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Wagemakers, J., Prynne, C., Stephen, A. et al. Consumption of red or processed meat does not predict risk factors for coronary heart disease; results from a cohort of British adults in 1989 and 1999. Eur J Clin Nutr 63, 303–311 (2009). https://doi.org/10.1038/sj.ejcn.1602954
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DOI: https://doi.org/10.1038/sj.ejcn.1602954
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