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SET domain proteins reSET gene expression

Histone methylation regulates the transcriptional activity of genes in the chromatin fiber and might provide a mechanistic basis for inheritable epigenetic patterns of gene transcription.

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Figure 1: Methylated lysine residues in the N-terminal tails of histones H3 and H4.
Figure 2: The scheme shows an epigenetic DNA element, containing Polycomb/trithorax group response elements (PRE/TRE), that regulates the expression of a nearby target gene.

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Correspondence to Valerio Orlando.

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Breiling, A., Orlando, V. SET domain proteins reSET gene expression. Nat Struct Mol Biol 9, 894–896 (2002). https://doi.org/10.1038/nsb1202-894

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