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Open season on RNA polymerase

Bacterial RNA polymerase holoenzyme and open complex structures reveal how the σ subunit binds RNA polymerase and mediates the specific recognition of promoter DNA to facilitate transcription initiation.

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Figure 1: Schematics of the overall structure of the σ subunit and RNA polymerase.

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Hsu, L. Open season on RNA polymerase. Nat Struct Mol Biol 9, 502–504 (2002). https://doi.org/10.1038/nsb0702-502

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