The treatment of primary sclerosing cholangitis is a major challenge. Complications such as dominant bile duct stenoses and biliary infections are associated with poor outcomes. Data from a new prospective study with a follow-up of 20 years now show that dominant stenosis and fungal, but not bacterial infections reduce survival free of liver transplantation.
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Tischendorf, J., Schirin-Sokhan, R. The importance of treating stenoses and infections. Nat Rev Gastroenterol Hepatol 6, 691–692 (2009). https://doi.org/10.1038/nrgastro.2009.181
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DOI: https://doi.org/10.1038/nrgastro.2009.181