Not all axons in a peripheral nerve are myelinated. A recent study shows that the expression of neuregulin-1 on an axon membrane determines whether immature Schwann cells will differentiate into myelinating Schwann cells.
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Nave, KA., Schwab, M. Glial cells under remote control. Nat Neurosci 8, 1420–1422 (2005). https://doi.org/10.1038/nn1105-1420
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DOI: https://doi.org/10.1038/nn1105-1420
