In this issue, the Withers laboratory takes advantage of the negatively charged sialic acid to develop a high-throughput screening technology that can be used for evolving glycosyltransferases with new enzymatic activities.
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References
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Wang, P. The charged sialic acid exhibits its power again: a new high-throughput screening technology. Nat Methods 3, 589–590 (2006). https://doi.org/10.1038/nmeth0806-589
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DOI: https://doi.org/10.1038/nmeth0806-589
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