Nature Medicine homepage
Advanced search
 Journal home > Archive > Table of Contents > News and Views > Abstract
Journal home
Advance online publication
Current issue
Archive
Press releases
Supplements
Focuses
Guide to authors
Online submissionOnline submission
For referees
Free online issue
Contact the journal
Subscribe
Advertising
work@npg
Reprints and permissions
About this site
For librarians
 
NPG Resources
Nature
Nature Reviews
Nature Immunology
Nature Cell Biology
Nature Genetics
news@nature.com
Nature Conferences
Dissect Medicine
NPG Subject areas
Biotechnology
Cancer
Chemistry
Clinical Medicine
Dentistry
Development
Drug Discovery
Earth Sciences
Evolution & Ecology
Genetics
Immunology
Materials Science
Medical Research
Microbiology
Molecular Cell Biology
Neuroscience
Pharmacology
Physics
Browse all publications
News and Views
Nature Medicine  8, 787 - 789 (2002)
doi:10.1038/nm0802-787

Protect the killer: CTLs need defenses against the tumor

Gordon J. Freeman1, Arlene H. Sharpe2 & Vijay K. Kuchroo3

1  Department of Adult Oncology, Dana-Farber Cancer Institute, Harvard Medical School Boston, Massachusetts, USA

2  Department of Pathology, Harvard Medical School Boston, Massachusetts, USA

3  Center for Neurologic Diseases, Brigham and Women's Hospital, Harvard Medical School Boston, Massachusetts, USA kuchroo@rics.bwh.harvard.edu

Evasion of the immune system is an all too common feature of cancer. A new study suggests one evasion mechanism: induction of T-cell apoptosis through B7-H1, a molecule expressed on the surface of many tumor cells (pages 793−800).

MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated

REFERENCE
Immunoregulation
Nature Encyclopaedia of Life Sciences
 See all 8 matches for Reference

REVIEWS
THE B7–CD28 SUPERFAMILY
Nature Reviews Immunology Review (01 Feb 2002)
 See all 24 matches for Reviews

NEWS AND VIEWS
More negative feedback?
Nature Immunology News and Views (01 Jul 2003)
T-cell stimulation: an abundance of B7s
Nature Medicine News and Views (01 Dec 1999)
 See all 7 matches for News And Views

RESEARCH
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
Nature Medicine Article (01 Aug 2002)
The B7 family member B7-H3 preferentially down-regulates T helper type 1–mediated immune responses
Nature Immunology Article (01 Sep 2003)
 See all 39 matches for Research

 Top
Abstract
Previous | Next
Table of contents
Full textFull text
Download PDFDownload PDF
Send to a friendSend to a friend
Save this linkSave this link

naturejobs

More science jobs
Post a job for free
Figures & Tables
See also: Article by Dong et al.
Export citation
natureproducts

Search buyers guide:

 
ADVERTISEMENT
 
Nature Medicine
ISSN: 1078-8956
EISSN: 1546-170X		 Journal home | Advance online publication | Current issue | Archive | Press releases | Supplements | Focuses | For authors | Online submission | For referees | Free online issue | About the journal | Contact the journal | Subscribe | Advertising | work@npg | Reprints and permissions | About this site | For librarians
Nature Publishing Group, publisher of Nature, and other science journals and reference works©2002 Nature Publishing Group | Privacy policy