Nature Medicine
9, 644 - 645 (2003)
doi:10.1038/nm0603-644
Lamin mutations come of ageRobert A Hegele
The author is in the Blackburn Cardiovascular Genetics Laboratory, Robarts Research Institute, London, Ontario N6A 5K8, Canada. hegelerobarts.ca
Mutations in the gene that encodes nuclear lamins A and C cause a host of diseases, ranging from dilated cardiomyopathy to lipid disorders. The aging syndrome, Hutchinson-Gilford progeria, is now added to the list.
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