Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Stopping malaria parasites dead in their tracks

Nature Chemical Biology volume 4, pages 334–335 (2008)Cite this article

The search for new antimalarial strategies takes a step forward with the discovery of a small parasitocidal molecule that inhibits a calcium-dependent protein kinase and may thereby interfere with parasite motility.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: The roles of CDPKs in the life cycle of malaria parasites.

Kim Caesar

References

  1. Ventura, J.J. & Nebreda, A.R. Clin. Transl. Oncol. 8, 153–160 (2006).

    Article  CAS  Google Scholar 

  2. Kato, N. et al. Nat. Chem. Biol. 4, 347–356 (2008).

    Article  CAS  Google Scholar 

  3. Soldati, D. & Meissner, M. Curr. Opin. Cell Biol. 16, 32–40 (2004).

    Article  CAS  Google Scholar 

  4. Green, J.L. et al. J. Mol. Biol. 355, 933–941 (2006).

    Article  CAS  Google Scholar 

  5. Dorin-Semblat, D. et al. Mol. Microbiol. 65, 1170–1180 (2007).

    Article  CAS  Google Scholar 

  6. Davies, S.P., Reddy, H., Caivano, M. & Cohen, P. Biochem. J. 351, 95–105 (2000).

    Article  CAS  Google Scholar 

  7. Bishop, A.C., Buzko, O. & Shokat, K.M. Trends Cell Biol. 11, 167–172 (2001).

    Article  CAS  Google Scholar 

  8. Billker, O. et al. Cell 117, 503–514 (2004).

    Article  CAS  Google Scholar 

  9. Ishino, T., Orito, Y., Chinzei, Y. & Yuda, M. Mol. Microbiol. 59, 1175–1184 (2006).

    Article  CAS  Google Scholar 

  10. Coppi, A. et al. Cell Host Microbe 2, 316–327 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Christian D. Doerig is at Institut National de la Santé et de la Recherche Médicale Unit 609, Wellcome Centre for Molecular Parasitology, University of Glasgow Biomedical Research Centre, 120 University Place, Glasgow, Scotland G12 8TA, UK. cdoer001@udcf.gla.ac.uk ,

    Christian D Doerig

Authors
  1. Christian D Doerig
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Doerig, C. Stopping malaria parasites dead in their tracks. Nat Chem Biol 4, 334–335 (2008). https://doi.org/10.1038/nchembio0608-334

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio0608-334

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing