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Pins for spines

Neurotransmitter receptors must be targeted to the post-synaptic membrane to perform their function in synaptic transmission. Recent findings reveal a surprising role for heterotrimeric G proteins and their activator, Pins (Partner of Inscuteable), in this important protein targeting event.

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Figure 1: A model of Pins function in NMDA receptor trafficking.

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Knoblich, J. Pins for spines. Nat Cell Biol 7, 1157–1158 (2005). https://doi.org/10.1038/ncb1205-1157

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