The expanding use of small RNA technology to silence specific genes shows no signs of slowing down. However, the discovery that it can induce components of the interferon system in animal cells should make us pause to consider potential non-specific effects of this technique.
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Moss, E., Taylor, J. Small-interfering RNAs in the radar of the interferon system. Nat Cell Biol 5, 771–772 (2003). https://doi.org/10.1038/ncb0903-771
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DOI: https://doi.org/10.1038/ncb0903-771
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