Mass spectrometry can now measure the absolute concentrations of the majority of cellular proteins without labeling.
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Vogel, C., Marcotte, E. Absolute abundance for the masses. Nat Biotechnol 27, 825–826 (2009). https://doi.org/10.1038/nbt0909-825
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DOI: https://doi.org/10.1038/nbt0909-825
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