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Toward a new cash cow

Cloned cattle engineered to carry an artificial chromosome encoding human immunoglobulin genes are a significant leap toward the production of safer and more potent therapeutic antibodies.

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Figure 1: Multiple cycles of transfection, selection, and nuclear transfer (NT) will be necessary to generate cattle for the recombinant production of human polyclonal antibodies.

© Bob Crimi

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Echelard, Y., Meade, H. Toward a new cash cow. Nat Biotechnol 20, 881–882 (2002). https://doi.org/10.1038/nbt0902-881

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