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To be or not to BMP

Nature Genetics volume 28, pages 105–107 (2001)Cite this article

Three years after MADH4 (also known as SMAD4) was identified as a gene critical to juvenile polyposis, BMPR1A, encoding a receptor in the same pathway, has been identified as another susceptibility gene. The TGFβ/BMP superfamily of molecules has not only been shown to be defective in neoplasia but also in the non-cancer developmental syndromes primary pulmonary hypertension and hereditary hemorrhagic telangiectasia.

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Authors and Affiliations

  1. Clinical Cancer Genetics and Human Cancer Genetics Programs, Comprehensive Cancer Center, and Division of Human Genetics, Department of Internal Medicine, The Ohio State University, Columbus, 43210, Ohio, USA

    Charis Eng

  2. CRC Human Cancer Genetics Research Group, University of Cambridge, Cambridge, CB2 2QQ, United Kingdom

    Charis Eng

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  1. Charis Eng
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Eng, C. To be or not to BMP. Nat Genet 28, 105–107 (2001). https://doi.org/10.1038/88802

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