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CooA, CAP and allostery

The crystal structure of the CooA protein yields potential insight into the general mechanism of allostery within the CAP family of transcriptional regulators.

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Figure 1: Mechanisms of regulation by the CAP family of transcriptional regulators.
Figure 2: Structures of CAP proteins in different conformational states.

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Acknowledgements

I would like to thank W. Lanzilotta and T. Poulos for access to the atomic coordinates.

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Chan, M. CooA, CAP and allostery. Nat Struct Mol Biol 7, 822–824 (2000). https://doi.org/10.1038/79559

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