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Signal transduction

Aspirin, ubiquitin and cancer

Tumours sidestep the body's rules and regulations in myriad ways. The latest discovery ties together a benign tumour syndrome with two hot subjects of biological research: the proteins NF-κB and ubiquitin.

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Figure 1: The well-characterized NF-κB signalling pathway, and a new contributor.

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Wilkinson, K. Aspirin, ubiquitin and cancer. Nature 424, 738–739 (2003). https://doi.org/10.1038/424738a

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