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Nucleotide sequence homology at 12 intron–exon junctions in the chick ovalbumin gene

Abstract

A short partial sequence homology is present at all intron–exon junctions, or splice points, in the chick ovalbumin gene; it is probably a signal for a splicing enzyme. The significance of the junction sequences for splicing is discussed. We find no evidence of strong Watson–Crick base pairing between adjacent junctions.

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Catterall, J., O'Malley, B., Robertson, M. et al. Nucleotide sequence homology at 12 intron–exon junctions in the chick ovalbumin gene. Nature 275, 510–513 (1978). https://doi.org/10.1038/275510a0

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