Abstract
Human oocytes have been matured and fertilized by spermatozoa in vitro. There may be certain clinical and scientific uses for human eggs fertilized by this procedure.
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References
Edwards, R. G., Lancet, ii, 926 (1965).
Edwards, R. G., Donahue, R. P., Baramki, T. A., and Jones, H. W., Amer. J. Obstet. Gynec., 96, 192 (1966).
Yanagimachi, R., and Chang, M. C., J. Exp. Zool., 156, 361 (1964).
Barros, C., and Austin, C. R., J. Exp. Zool., 166, 317 (1967).
Bavister, B. D., J. Reprod. Fertil. (in the press).
Williams, W. L., Weinman, D. E., and Hamner, C. E., Fifth Intern. Cong. Anim. Reprod. A.I., Trento, 7, 288 (1964).
Brinster, R. L., Exp. Cell Res., 32, 205 (1963).
Dickmann, Z., Clewe, T. H., Bonney, W. A., and Noyes, B. W., Anat. Rec., 152, 293 (1965).
Whittingham, D. G., Nature, 220, 592 (1968).
Whitten, W. K., and Biggers, J. D., J. Reprod. Fertil., 17, 399 (1968).
Austin, C. R., The Mammalian Egg (Blackwell, Oxford, 1961).
Chang, M. C., J. Exp. Zool., 128, 379 (1955).
Davidson, E., Allfrey, V. G., and Mirsky, A. E., Proc. US Nat. Acad. Sci., 52, 501 (1964).
Edwards, R. G., Nature, 208, 349 (1965).
Jagiello, G., Karnicki, J., and Ryan, R. J., Lancet, i, 178 (1968).
Henderson, S. A., and Edwards, R. G., Nature, 218, 22 (1968).
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EDWARDS, R., BAVISTER, B. & STEPTOE, P. Early Stages of Fertilization in vitro of Human Oocytes Matured in vitro. Nature 221, 632–635 (1969). https://doi.org/10.1038/221632a0
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DOI: https://doi.org/10.1038/221632a0
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