Analyses of the Alzheimer's disease β-amyloid peptide are revealing the chemical basis for its propensity to form insoluble neurotoxic fibrils and suggest an intriguing link between the free radical theory of neurodegenerative disorders and the chemistry of amyloidogenic peptides.
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Mattson, M. Untangling the pathophysio-chemistry of β-amyloid. Nat Struct Mol Biol 2, 926–928 (1995). https://doi.org/10.1038/nsb1195-926
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DOI: https://doi.org/10.1038/nsb1195-926
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