Nature 286, 33 - 39 (03 July 1980); doi:10.1038/286033a0

Structure of southern bean mosaic virus at 2.8 Å resolution

Celerino Abad-Zapatero, Sherin S. Abdel-Meguid, John E. Johnson, Andrew G. W. Leslie^*, Ivan Rayment^†, Michael G. Rossmann, Dietrich Suck^‡ & Tomitake Tsukihara^§

Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907
Present addresses: ^* Biophysics Section, Blackett Laboratory, Imperial College of Science and Technology, Prince Consort Road, London SW7 2BZ, UK; ^† Structural Biology Laboratory, Rosenstiel Basic Medical Sciences Research Center, Brandeis University, Waltham, Massachusetts 02154; ^‡ European Molecular Biology Laboratory, Postfach 10 22 09, 69 Heidelberg 1, FRG; ^§ Department of Chemistry, Faculty of Engineering, Tottori University, Koyama-cho, Tottori 680, Japan.

X-ray diffraction studies reveal that the polypeptide chain of the southern bean mosaic virus protein subunit has a fold closely similar to the shell domain of tomato bushy stunt virus. The protruding domain of tomato bushy stunt virus is absent in southern bean mosaic virus. The tertiary structure observed in these viruses may be particularly suitable f or the formation of the protein coat in small, spherical, RNA-containing, plant viruses.

References

1.	Crick, F. H. C. & Watson, J. D. Nature 177, 473−475 (1956). | PubMed | ISI | ChemPort |
2.	Caspar, D. L. D. & Klug, A. Cold Spring Harb. Symp. quant. Biol. 27, 1−24 (1962). | PubMed | ISI | ChemPort |
3.	Fraenkel-Conrat, H. in Comprehensive Virology Vol. 1 (eds Fraenkel-Conrat, H. & Wagner, R. R.) 1−191 (Plenum, New York, 1974).
4.	Commonwealth Mycological Institute and Association of Applied Biologists Descriptions of Plant Viruses (Commonwealth Mycological Institute, Surrey, 1970).
5.	Stubbs, G., Warren, S. & Holmes, K. Nature 267, 216−221 (1977). | PubMed | ISI | ChemPort |
6.	Bloomer, A. C., Champness, J. N., Bricogne, G., Staden, R. & Klug, A. Nature 276, 362−368 (1978). | ISI | ChemPort |
7.	Harrison, S. C., Olson, A. J., Schutt, C. E., Winkler, F. K. & Bricogne, G. Nature 276, 368−373 (1978). | ISI | ChemPort |
8.	White, J. M. & Johnson, J. E. Virology 101, 319−324 (1980). | Article | ISI |
9.	Hull, R. J. gen. Virol. 36, 289−295 (1977). | ISI |
10.	Argos, P. in Proc. 7th Aharon Katzir−Katchalsky Conf., Rehovot (in the press).
11.	Akimoto, T., Wagner, M. A., Johnson, J. E. & Rossmann, M. G. J. ultrastruct. Res. 53, 306−318 (1975). | PubMed | ISI | ChemPort |
12.	Arndt, U. W. & Wonacott, A. J. The Rotation Method in Crystallography (North-Holland, Amsterdam, 1977).
13.	Rossmann, M. G. J. appl. Crystallogr. 12, 225−238 (1979). | Article | ISI | ChemPort |
14.	Rossmann, M. G., Leslie, A. G. W., Abdel-Meguid, S. S. & Tsukihara, T. J. appl. Crystallogr. 12, 570−581 (1979). | Article | ISI | ChemPort |
15.	Leslie, A. G. W. & Tsukihara, T. J. appl. Crystallogr. (in the press).
16.	Harrison, S. C. J. appl. Crystallogr. 1, 84−90 (1968). | Article | ISI |
17.	Rayment, I., Johnson, J. E., Suck, D., Akimoto, T. & Rossmann, M. G. Acta crystallogr. B34, 567−578 (1978). | ISI |
18.	Suck, D., Rayment, I., Johnson, J. E. & Rossmann, M. G. Virology 85, 187−197 (1978). | Article | PubMed | ISI | ChemPort |
19.	Rossmann, M. G. Acta crystallogr. A32, 774−777 (1976). | Article | ISI |
20.	Abad-Zapatero, C. et al. Acta crystallogr. (submitted).
21.	Johnson, J. E. Acta crystallogr. B34, 576−577 (1978).
22.	Buehner, M., Ford, G. C., Moras, D., Olsen, K. W. & Rossmann, M. G. J. molec. Biol. 82, 563−585 (1974). | PubMed | ISI | ChemPort |
23.	Bricogne, G. Acta crystallogr. A30, 395−405 (1974). | Article | ChemPort |
24.	Argos, P., Ford, G. C. & Rossmann, M. G. Acta crystallogr. A31, 499−506 (1975). | Article | ISI |
25.	Winkler, F. K., Schutt, C. E., Harrison, S. C. & Bricogne, G. Nature 265, 509−513 (1977). | PubMed | ISI | ChemPort |
26.	Richardson, J. S. Nature 268, 495−500 (1977). | PubMed | ISI | ChemPort |
27.	Richards, F. M. J. molec. Biol. 37, 225−230 (1968). | PubMed | ISI | ChemPort |
28.	Bernstein, F. C. et al. J. molec. Biol. 112, 535−542 (1977). | PubMed | ISI | ChemPort |
29.	Dickerson, R. E. & Geis, I. The Structure and Action of Proteins (Harper & Row, New York, 1969).
30.	Johnson, J. E., Akimoto, T., Suck, D., Rayment, I. & Rossmann, M. G. Virology 75, 394−400 (1976). | Article | PubMed | ISI | ChemPort |
31.	Hsu, C. H., White, J. A. & Sehgal, O. P. Virology 81, 471−475 (1977). | Article | PubMed | ISI | ChemPort |
32.	Sehgal, O. P. & Sinha, R. C. Virology 59, 499−508 (1974). | PubMed | ISI | ChemPort |
33.	Hull, R. Virology 89, 418−422 (1978). | Article | ISI | ChemPort |
34.	Rayment, I., Johnson, J. E. & Rossmann, M. G. J. biol. Chem. 254, 5243−5245 (1979). | PubMed | ISI | ChemPort |
35.	Wells, J. M. & Sisler, H. D. Phytopathology 58, 1588−1592 (1968). | PubMed | ISI | ChemPort |
36.	Tremaine, J. H. Virology 30, 348−354 (1966). | Article | PubMed | ISI | ChemPort |
37.	Ghabrial, S. A., Shepherd, R. J. & Grogan, R. G. Virology33, 17−25 (1967). | Article | PubMed | ISI | ChemPort |
38.	Dietrich, J. B. thesis, Univ. Louis Pasteur de Strasbourg (1979).
39.	Chauvin, C., Witz, J. & Jacrot, B. J. molec. Biol. 124, 641−651 (1978). | PubMed | ISI | ChemPort |
40.	Sehgal, O. P., Hsu, C. H., White, J. A. & Van, M. Phytopath. Z. 95, 167−177 (1979). | ISI |
41.	Tremaine, J. H. & Ronald, W. P. Virology 91, 164−172 (1978). | Article | PubMed | ISI | ChemPort |
42.	Pfeiffer, P. & Hirth, L. FEBS Lett. 56, 144−148 (1975). | Article | PubMed | ISI | ChemPort |
43.	Leberman, R. & Finch, J. T. J. molec. Biol. 50, 209−213 (1970). | Article | PubMed | ISI | ChemPort |
44.	Crowther, R. A. & Amos, L. A. Cold Spring Harb. Symp. quant. Biol. 36, 489−494 (1972). | PubMed | ISI | ChemPort |
45.	Bol, J. F., Kraal, B. & Brederode, F. Th. Virology 58, 101−110 (1974). | Article | PubMed | ISI | ChemPort |
46.	Warrant, R. W. & Kim, S. H. Nature 271, 130−135 (1978). | PubMed | ISI | ChemPort |
47.	Thomas, J. O. Int. Rev. Biochem. 17, 181−232 (1978). | ChemPort |
48.	Moss, T., Cary, P. D., Crane-Robinson, C. & Bradbury, E. M. Biochemistry 15, 2261−2267 (1976). | PubMed | ISI | ChemPort |
49.	Lilley, D. M. J., Howarth, O. W., Clark, V. M., Pardon, J. F. & Richards, B. M. FEBS Lett. 62, 7−10 (1976). | Article | PubMed | ISI | ChemPort |
50.	Unge, T. et al. Nature 285, 373−377 (1980). | Article | ISI | ChemPort |
51.	Argos, P., Tsukihara, T. & Rossmann, M. G. J. molec. Evolut. (in the press).
52.	Rossmann, M. G. & Argos, P. J. molec. Biol. 109, 99−129 (1977). | PubMed | ISI | ChemPort |