Abstract
There is evidence to suggest that the infectious disease scrapie is caused by an agent which does not depend on a nucleic acid for its ability to replicate. In the first of the two following articles it is suggested that scrapie can best be considered to arise from a replicable change in the structural pattern of a commonly occurring unit membrane. In the second article it is suggested that the agent is a protein and three possible mechanisms for its self-replication are proposed.
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GIBBONS, R., HUNTER, G. Nature of the Scrapie Agent. Nature 215, 1041–1043 (1967). https://doi.org/10.1038/2151041a0
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DOI: https://doi.org/10.1038/2151041a0
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