Collection

On Growth and Form Centenary

  • Nature Physics | Letter

    A 3D-printed fetal brain undergoes constrained expansion to reproduce the shape of the human cerebral cortex. The soft gels of the model swell in solvent, mimicking cortical growth and revealing the mechanical origin of the brain’s folded geometry.

    • Tuomas Tallinen
    • , Jun Young Chung
    • , François Rousseau
    • , Nadine Girard
    • , Julien Lefèvre
    •  &  L. Mahadevan
  • Nature Ecology & Evolution | Article

    Variation around colour pattern genes is highly modular in Heliconius butterflies. This modular architecture explains the diversity of colour patterns and provides a flexible mechanism for rapid morphological diversification.

    • Steven M. Van Belleghem
    • , Pasi Rastas
    • , Alexie Papanicolaou
    • , Simon H. Martin
    • , Carlos F. Arias
    • , Megan A. Supple
    • , Joseph J. Hanly
    • , James Mallet
    • , James J. Lewis
    • , Heather M. Hines
    • , Mayte Ruiz
    • , Camilo Salazar
    • , Mauricio Linares
    • , Gilson R. P. Moreira
    • , Chris D. Jiggins
    • , Brian A. Counterman
    • , W. Owen McMillan
    •  &  Riccardo Papa
  • Nature Ecology & Evolution | Article

    Domesticated animals are great models to understand how diversity is generated. Here, the authors show that patterns of cranial shape variation in domestic pigeons mirror cranial variation in birds in general, suggesting that selection on conserved developmental mechanisms can generate tremendous diversity.

    • Nathan M. Young
    • , Marta Linde-Medina
    • , John W. Fondon
    • , Benedikt Hallgrímsson
    •  &  Ralph S. Marcucio
  • Nature Cell Biology | Article

    Orhon et al. report that primary-cilium-mediated fluid flow sensing triggers autophagy through LKB1–AMPK–mTOR signalling, and thereby controls the volume of kidney epithelial cells.

    • Idil Orhon
    • , Nicolas Dupont
    • , Mohamad Zaidan
    • , Valérie Boitez
    • , Martine Burtin
    • , Alain Schmitt
    • , Thierry Capiod
    • , Amandine Viau
    • , Isabelle Beau
    • , E. Wolfgang Kuehn
    • , Gérard Friedlander
    • , Fabiola Terzi
    •  &  Patrice Codogno
  • Nature Communications | Article

    Interphase microtubule organization creates a structural scaffold for cargo delivery determining cell polarity and cell shape. Here the authors show that in Drosophila epithelia the orientation of microtubules responds to cell shape, rather than the converse, and develop a simple model to mimic this behaviour.

    • Juan Manuel Gomez
    • , Lyubov Chumakova
    • , Natalia A. Bulgakova
    •  &  Nicholas H. Brown
  • Nature Communications | Article

    EpCAM is an unconventional epithelia-specific cell–cell adhesion molecule, that is mutated in the majority of cases of Congenital Tufting Enteropathy. Here the authors show that loss of EpCAM causes a concentration of contractile activity at tricellular junctions, leading to aberrant apical domain and tight junction displacement.

    • Julie Salomon
    • , Cécile Gaston
    • , Jérémy Magescas
    • , Boris Duvauchelle
    • , Danielle Canioni
    • , Lucie Sengmanivong
    • , Adeline Mayeux
    • , Grégoire Michaux
    • , Florence Campeotto
    • , Julie Lemale
    • , Jérôme Viala
    • , Françoise Poirier
    • , Nicolas Minc
    • , Jacques Schmitz
    • , Nicole Brousse
    • , Benoit Ladoux
    • , Olivier Goulet
    •  &  Delphine Delacour