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Stem Cells and Tissue Regeneration

Use of adult marrow mesenchymal stem cells for regeneration of cardiomyocytes

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Bone marrow cells have been suggested to have multilineage plasticity including formation of cardiac tissue. We have established a cardiomyogenic (CMG) cell line from mouse bone marrow stromal cells that can be induced to differentiate into cardiomyocytes in vitro by 5-azacytidine treatment. A number of lines of evidence confirm the cardiomyocyte characteristics of CMG cells.

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Fukuda, K. Use of adult marrow mesenchymal stem cells for regeneration of cardiomyocytes. Bone Marrow Transplant 32 (Suppl 1), S25–S27 (2003). https://doi.org/10.1038/sj.bmt.1703940

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  • DOI: https://doi.org/10.1038/sj.bmt.1703940

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