1. ¹Department of Epidemiology, Harvard School of Public Health, Boston, MA, USA
2. ²Channing Laboratory, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA
3. ³Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
4. ⁴Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA
5. ⁵Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutions, Baltimore, MD, USA
6. ⁶Department of Nutrition, Harvard School of Public Health, Boston, MA, USA

Correspondence: Professor DS Michaud, Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Kresge 920, Boston, MA 02115, USA. E-mail: dmichaud@hsph.harvard.edu

Received 26 September 2006; Revised 30 October 2006; Accepted 8 November 2006; Published online 12 December 2006.

Abstract

In a prospective cohort study, a close to two-fold elevated risk of bladder cancer was found among men reporting a history of gonorrhoea (relative risk=1.92, 95% CI=1.10–3.33). Our finding warrants further examination of the role of gonorrhoea in bladder carcinogenesis.