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BJC Open article

British Journal of Cancer (2005) 93, 849–854. doi:10.1038/sj.bjc.6602754 www.bjcancer.com
Published online 27 September 2005

Proton beam therapy

W P Levin1, H Kooy1, J S Loeffler1 and T F DeLaney1

1Massachusetts General Hospital Northeast Proton Therapy Center, Boston, MA 02114, USA

Correspondence: Dr TF DeLaney, E-mail: TDELANEY@PARTNERS.ORG

Received 12 May 2005; Revised 29 July 2005; Accepted 29 July 2005
Advance online publication 27 September 2005

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Abstract

Conventional radiation therapy directs photons (X-rays) and electrons at tumours with the intent of eradicating the neoplastic tissue while preserving adjacent normal tissue. Radiation-induced damage to healthy tissue and second malignancies are always a concern, however, when administering radiation. Proton beam radiotherapy, one form of charged particle therapy, allows for excellent dose distributions, with the added benefit of no exit dose. These characteristics make this form of radiotherapy an excellent choice for the treatment of tumours located next to critical structures such as the spinal cord, eyes, and brain, as well as for paediatric malignancies.

Keywords:

radiotherapy; protein beam

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