In this study, IOTN and OHRQoL are positively correlated.

Kunz F, Platte P, Kess S et al. J Orofac Orthop 2018; 79: 297–308

There is little available data on the correlation between misaligned teeth and jaws, and oral health-related quality of life (OHRQoL)t

This questionnaire-based study recruited 250 young people (aged 7-17, mean 12.15 years, SD 2.02) and recorded data concerning self esteem, quality of life, OHRQoL, behavioural problems and the Index of Orthodontic Treatment Need (IOTN).

There was no significant correlation between OHQRoL and gender, body mass index and socio-economic status. Behavioural problems and a lack of self-esteem were significantly correlated with OHQRoL. There was no correlation between OHQRoL and those patients who felt a subjective need for treatment on aesthetic grounds. There was however a positive correlation between those who were objectively described as needing orthodontic treatment by an orthodontist on both the dental health component of IOTN and the aesthetic index used.