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Merchant SN, Vovk A et al. J Periodontol 2014; 85: 1722–1729

It was stated that the research aim was to compare treatment outcomes in patients with localised aggressive periodontitis affecting their primary dentition (n = 22, 15 completed the study) with treatment outcomes in other patients with localised aggressive periodontitis in their secondary dentition (n = 75, only 36 completed the study). As to the thorny issue of diagnosis of localised aggressive periodontitis, among other criteria, it had to involve at least two teeth that included an incisor or molar tooth, probing depth >5 mm with bleeding on probing, and radiographic bone loss. All patients were African Americans with unremarkable medical histories. Periodontal treatment comprised full-mouth mechanical debridement at baseline 3, 6, and 12 months. At the first appointment, systemic antibiotics were prescribed. The antibiotic regimen comprised 500 mg amoxicillin and 250 mg metronidazole, three times a day for 7 days. More favourable treatment outcomes were observed in those with localised periodontal treatment in the primary dentition.