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Bonafé E, Loguercio A D et al. Clin Oral Investig 2014; 18: 839–845

High concentrations of bleaching agents (35% hydrogen peroxide) do not confer superior whitening of teeth when compared with at-home bleaching with 10% carbamide peroxide (Int J Periodont Restor Dent 2012; 32: 303–309). In the UK, 6% hydrogen peroxide (16% carbamide peroxide) is the maximum permitted concentration. The aim of this study was to find out if the use of a desensitizing gel reduced sensitivity following 'in office' bleaching. This study, carried out in Brazil, recruited 30 volunteers. The conditions used to evoke sensitivity were severe with the use of 35% hydrogen peroxide gel over two 45 minute appointments. In addition, each subject had up to five anterior composite restorations with the inevitable associated leakage. Tooth sensitivity was recorded daily for 7 days only, following bleaching. Irrespective of the use of a desensitising gel, all subjects experienced sensitivity, particularly from the lateral incisor teeth. However, the intensity of sensitivity was less in the test group. Satisfactory bleaching was achieved after 2 weeks with no 'color rebound' at 6 months.