Abstract
In intact humans, deprivation of somatosensory and kinesthetic sensations result in significant alterations in perception and information processing. There have been very few studies to discover if the loss of sensation with spinal cord injury (SCI) in humans affects perceptual operations. We hypothesized that the SCI participant would either exhibit arousal, perceptual, and information processing alterations similar to experimentally sensory deprived subjects (who provide the closest human analogue), or that the somatosensory cortex would show reorganization for the processing of other modalities of stimulation.
The subjects consisted of 16 paraplegic, 13 quadriplegic, and 22 non SCI controls. Subjects received an auditory orienting task consisting of a 500 Hz tone presented 20 times each at 66, 75, 88, and 101 db and a visual orienting task incorporating light flashes of 115, 123, 131, and 140 lux presented 20 times each. EEG information processing data were recorded from C3 and C4 for 100 msec prior to and 500 msec post stimulation
Information processing variables, analyzed as event-related potentials, indicated that the somatosensory cortex of SCI groups had a flattened response to auditory stimulation. The control group had a significantly larger P2 component. We concluded that these data signified that the somatosensory cortex did not reorganize function in response to chronic deafferentation nor was the SCI subject hyperresponsive to stimulation.
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References
Zuckerman M, Hopkins T R (1966) Hallucinations or dreams? A study of arousal levels and reported visual sensations during sensory deprivation. Perceptual and Motor Skills 22: 447–459.
Heron W (1957) The pathology of boredom. Scientific American 196: 52–56.
Heron W (1961) Cognitive and physiological effects of perceptual isolation. In: P Solomon et al, editors. Sensory Deprivation. Cambridge MA: Harvard University Press, Cambridge MA: 6–33.
Heron W, Tait G, Smith G K (1972) Effects of prolonged isolation of the human electroencephalogram. Brain Res 43: 280–284.
Zubek J P, Hughes G R, Shephard J M (1971). A comparison of the effects of prolonged sensory deprivation and perceptual deprivation. Can J Behav Sci 3: 282–290.
Zubek J P, Welch G (1963) Electroencephalographic changes after prolonged sensory and perceptual deprivation. Science 139: 1209–1210.
Braunstein P (1957) Perceptual changes following isolation of a limited tactual area. Unpublished thesis cited in JP Zubek (1969) Sensory Deprivation: 15 Years of Research. Appleton-Century-Crofts, New York.
Aftanas M, Zubek J P (1963) Effects of prolonged isolation of the skin on cutaneous sensitivity. Perceptual and Motor Skills 16: 565–571.
Aftanas M, Zubek J P (1963) Long-term effects following isolation of a circumscribed area of the skin. Perceptual and Motor Skills 17: 867–870.
Zubek J P (1969) Sensory and perceptual-motor process. In: Zubek JP, editor. Sensory Deprivation: 15 Years of Research. Appleton-Century-Crofts, New York.
Stavraky G W (1961) Supersensitivity Following Lesions of the Nervous System. University of Toronto Press, Toronto.
Zubek J P, Aftanas M, Kovach K, Wilgosh L, Winocur G (1963) Effect of severe immobilization of the body on intellectual and perceptual processes. Can J Psychol 17: 118–133.
Adey W R, Bors E, Porter R W (1968) EEG sleep patterns after high cervical lesions in man. Arch Neurol 19: 337–383.
Itil T M, Saletu B, Marasa J (1972) Digital computer analyzed sleep electroencephalograms (sleep prints) in predicting anxiolytic properties of clorazepate dipotassium (tranxene). Curr Ther Res 14: 415–427.
Richards J S, Hirt M, Malamed L (1982) Spinal cord injury: a sensory restriction perspective. Arch Phys Med Rehabil 63: 195–199.
Hester G A (1971) Effects of functional transection of spinal cord on task performance under varied emotional conditions. Psychophysiology 8: 451–461.
Richards J S, Seitz M R, Eisele W A (1986) Auditory processing in spinal cord injury: A preliminary investigation from a sensory deprivation perspective. Arch Phys Med Rehabil 67: 115–117.
Merzenich M M, Nelson R J, Stryker M P, Cyander M S, Schoppmann A, Zook J M (1984) Somatosensory cortical map changes following digit amputation in adult monkeys. J Compar Neurol 224: 591–605.
Neville H, Kutas M, Schmidt A (1982) Event-related potential studies of cerbral specialization during reading: II. Studies of congenitally deaf adults. Brain and Language 16: 316–337.
Neville H, Shmidt A, Kutas M (1983) Altered vision-evoked potentials in congenitally deaf adults. Brain Res 266: 127–132.
Regan D (1989) Human Brain Electrophysiology: Evoked Potentials and Evoked Magnetic Fields in Science and Medicine. Elsevier, New York.
Roth W T, Dorato K H, Kopell B S (1984) Intensity and Task effects on evoked physiological responses to noise burst. Psychophysiology 21: 488–481.
Goff W R, Allison T, Vaughan Jr H G (1978) The functional neuroanatomy of event-related potentials. In: Callaway E, Teuting P, Koslow S, editors. Event-related Brain Potentials in Man. Academic Press, New York: 1–79.
Midha R, Fehlings M G, Tator C H, Saint-Cyr J A, Guha A (1987) Assessment of spinal cord injury by counting corticospinal and rubrospinal neurons, Brain Res 410: 299–308.
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Cohen, M., Schandler, S. & Vulpe, M. Event-related brain potentials during orienting to auditory and visual stimulation in spinal cord injured humans. Spinal Cord 30, 864–871 (1992). https://doi.org/10.1038/sc.1992.163
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DOI: https://doi.org/10.1038/sc.1992.163